ResourceLife Sciences
Advancing GMP compliance with HTS: Robust virus detection in high virus, low host systems
9 Sept 2025This study highlights how short-read high-throughput sequencing (HTS), combined with QIAGEN® CLC Genomics Workbench, enables sensitive and reproducible detection of adventitious viruses in biologics. Conducted across seven global laboratories, the multi-lab investigation demonstrates HTS’s ability to enhance viral safety testing under GMP, supporting regulatory compliance and reducing reliance on traditional animal-based assays.
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QIAGEN CLC Genomics Workbench
QIAGENComplete toolkit for genomics, transcriptomics, epigenomics, and metagenomics in one program
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Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GMPRegulatory ComplianceBiologicsBiologics are medical products derived from living organisms, including vaccines, gene therapies, and monoclonal antibodies. These treatments are key to modern healthcare, especially in oncology and autoimmune diseases. Explore biologics research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Microbial DetectionMicrobial detection is crucial for identifying and quantifying bacteria, viruses, fungi, and other microorganisms. This process is essential for food safety, environmental monitoring, clinical diagnostics, and pharmaceutical manufacturing. Explore the best microbial detection tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.