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ACQUITY UPLC I-Class SM-FL/Xevo TQ-S micro IVD system: Analytical performance for immunosuppressive agents

23 Mar 2023

This application note focuses on the analytical performance of the ACQUITY™ UPLC™ I-Class SM-FL/Xevo™ TQ-S micro IVD System for the simultaneous analysis of four immunosuppressant drugs - cyclosporine, everolimus, sirolimus, and tacrolimus - in whole blood. The test is carried out to evaluate the system's ability to accurately and consistently quantify the target analytes in clinical samples, providing clinicians with reliable information to aid in the diagnosis and treatment of patients.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Organic CompoundsOrganic compounds are carbon-based molecules that form the building blocks of life. These include hydrocarbons, lipids, proteins, and nucleic acids. Understanding organic compounds is crucial in chemistry, biochemistry, and pharmacology. Explore organic compound analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Calibration