ResourceMaterials
Accurate and Repeatable Measurement of Fine Crystalline APIs using Laser Diffraction
12 May 2013Solid active pharmaceutical ingredients (APIs) are best to be measured in their original dry state in order to receive a reliable characterization of the particle size distribution. To achieve meaningful results from laser diffraction analysis, dosing and dispersion of the sample is performed by the dry dispersion system RODOS & VIBRI. Dispersed particles are being fed to the measuring zone of the modular laser diffraction sensor HELOS as a free aerosol jet. The particle size spectrum is determined with the highest degree of accuracy, repeatability and reproducibility.
Related products
Request Quote for All Products
HELOS | RODOS & Co. - Laser Diffraction Series
Sympatec GmbHModular laser diffraction sensor for laboratory analysis of particle size and distribution from below 0.1 µm to 8,750 µm
Links
Tags
Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Active PharmaceuticalsThe Active Pharmaceutical Ingredient (API) of a drug is the component that causes the direct effect of the product. The remaining inactive components are known as excipients.Powder Analysis