Accelerating the STR Analysis Workflow through Automation and Direct Amplification Methods

The PowerPlex® 21 System is a multiplex STR system for human identification applications including forensic analysis, relationship testing and research use.   The PowerPlex® 21 System is more tolerant of PCR inhibitors than other STR systems including the PowerPlex® 16 HS System. This allows more interpretable data and less need for re-amplification of samples previously deemed "difficult" due to the presence of inhibitors. The system allows co-amplification and fluorescent detection of 21 loci (20 STR loci and Amelogenin), including D1S1656, D2S1338, D3S1358, D5S818, D6S1043, D7S820, D8S1179, D12S391, D13S317, D16S539, D18S51, D19S433, D21S11, Amelogenin, CSF1PO, FGA, Penta D, Penta E, TH01, TPOX and vWA. The PowerPlex® 21 System is compatible with the ABI PRISM® 3100 and 3100-Avant Genetic Analyzers and Applied Biosystems® 3130, 3130xl, 3500 and 3500xL Genetic Analyzers. PowerPlex® 21 Features & Benefits:   Rapid thermal cycling, saving time with every run. Unbeatable inhibitor tolerance, enabling analysis of challenging casework samples. Optimized protocols for many sample types, including direct amplification from FTA® cards, as well as pretreated non FTA® card punches or swabs.