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Accelerate your translational workflows with effortless selectivity enhancements

13 Nov 2023

This application note from Thermo Fisher Scientific explores a seamless experimental workflow that overcomes sample complexity to maximize detection, characterization, and quantitation of biological compounds for putative biomarker determination. In the note, discover how the FAIMS Pro interface is a differential ion mobility device that seamlessly works with a broad range of Thermo Scientific™ next-generation mass spectrometers for identification and/or quantitation across a broad range of compounds. Differential ion mobility provides orthogonal selectivity to that of LC and MS, expanding breadth and depth of compound detection and quantitation. Introducing orthogonal selectivity at the ion source maximizes MS instrument capabilities for discovery and targeted analytical presents the FAIMS Pro interface for seamless biological mass spectrometry.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. HRAM
Accelerate your translational workflows with effortless selectivity enhancements