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AAV analytics with mass photometry

Refeyn
8 Jun 2023

Mass photometry is an innovative technology that analyzes biomolecules, including adeno-associated viruses (AAVs), at the single-particle level, in their native state and without the need for labels. In this application note, Refeyn shows that mass photometry is an ideal analytical technology for AAV research, development and manufacturing. In just minutes, a mass photometer can precisely measure the empty/full capsid ratio for AAVs of any serotype. It requires only very small sample volumes and concentrations, and minimal sample preparation.

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SamuxMP Auto

Refeyn

The SamuxMP Auto is the automated mass photometer for AAV characterization, autonomously measuring up to 24 samples in approximately 90 minutes. The instrument rapidly measures AAV empty/full ratios, sample purity, and particle aggregation for any AAV serotype – with high precision and reproducibility.

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SamuxMP

Refeyn

The Refeyn SamuxMP is a mass photometer optimised for adeno-associated virus (AAV) characterisation and is an essential analytical tool for laboratories working with AAVs. The SamuxMP precisely measures the empty/full capsid ratio for AAVs of any serotype. SamuxMP mass photometry measurements are rapid and require very little sample.

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MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Photometry

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AAV analytics with mass photometry