SelectScience
Join Free
Accelerating Science
ResourceLife Sciences

A Universal Surface Coating for Lab-On-A-Chip and Biosensor Applications

Anteo Technologies

A Universal Surface Coating for Lab-On-A-Chip and Biosensor Applications

5 Aug 2015

This poster describes an alternative to traditional methods of biomolecule attachment that utilizes a metal polymer surface chemistry. Various formulations of Mix&Go particles from Anteo Technologies can modify the strength of binding, wettability and surface charge, controlling protein binding and the stability of bound biomolecules. The coating was measured using SEM, TEM, AFM and other microscopic methods. Attaching biomolecules onto solid supports is a necessary step in developing and manufacturing most in vitro diagnostics and point-of care products. However, direct immobilization of antibodies to synthetic surfaces can damage proteins and adversely impact both their structure and function.

Related products

Request Quote for All Products

Mix&Go™ Biosensor

Anteo Technologies

Mix&Go Biosensor is a ready-to-use Activation Reagent specifically developed for binding biomolecules onto planar surfaces including polystyrenes, certain cyclic olefin copolymers, microarray slides, silicon oxides, titanium oxides, ceramics and gold surfaces (excluding gold colloids in suspension). Mix&Go Biosensor can modify the strength of binding, wettability and surface charge of base materials commonly used in biosensor applications. By using Mix&Go surface coatings, it is possible to control protein binding and improve the stability of bound biomolecules across a range of surfaces used in biosensors. Mix&Go Biosensor has many advantages over methods such as EDC, including: Mix&Go is water based and replaces the dry chemicals you would use with the EDC method Using Mix&Go instead of NHS/EDC chemistry can save up to 3-4 hours of lab time Increased stability of antibodies Higher functionality of antibodies Decreased background Mix&Go improves reproducibility between experiments by providing uniformity between surfaces.

(1)

Links

Anteo TechnologiesCompany website

Tags

AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Point of Care SolutionsPoint of care solutions provide medical diagnostics and treatments at or near the site of patient care. These technologies offer rapid results, helping healthcare providers make quick decisions. From glucose monitors to molecular diagnostics, point of care solutions are transforming healthcare delivery by reducing wait times and improving patient outcomes. Explore the best point of care products in our peer-reviewed product directory, compare options, check reviews, and get pricing directly from manufacturers.Sensor ChipIn Vitro DiagnosticsIn vitro diagnostics (IVD) involve testing samples outside the body, typically in a laboratory, to diagnose diseases or conditions. IVD technologies include blood tests, molecular assays, and other bodily fluid tests, enabling accurate diagnosis and monitoring of diseases. These tests are essential for guiding treatment decisions in clinical settings. Browse our peer-reviewed product directory to find the best IVD solutions; compare products, check reviews, and get pricing directly from manufacturers.

Related resources

A Universal Surface Coating for Lab-On-A-Chip and Biosensor Applications