A Study of Drug-Induced Liver Injury Using 3D Primary Human Hepatocytes
7 Dec 2018This application note demonstrates how 3D primary human hepatocyte (PHH) spheroids demonstrate increased sensitivity to drug-induced liver injury in comparison to 2D PHH monolayer culture.
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Corning Life SciencesUltra-Low Attachment microplates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment Surface minimizes protein absorption, enzyme activation and cellular activation Surface is noncytotoxic, biologically inert and nondegradable Sterilized by gamma irradiation Black wall microplates have low background fluorescence, minimal light scatter and reduced crosstalk Opaque walls to prevent well-to-well crosstalk Can be used for both top and bottom reading instruments Bulk packed 10 per bag Novel well geometry aids formation of spheroids in center of well Optically clear round bottom with black opaque microplate body
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