ResourceLife Sciences
A simple quantitative method for monoclonal antibody coformulations
14 Oct 2020Monoclonal antibodies (mAbs) are well-established therapeutics for biopharmaceutical work. However, recent trends have investigated the administration of multiple mAbs for immunotherapy and passive immunization strategies. Although characterization may present unique challenges, quantitation of each individual mAb tend to rely on standard analytical workflows, but methods for drug substance of the mAb coformulation often consist of a more complex analysis. One such consideration is a simple quantitative method for the mAb coformulation.
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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.ImmunotherapyImmunotherapy is a treatment approach that utilizes the body�s immune system to fight diseases, especially cancer. It includes therapies such as monoclonal antibodies, checkpoint inhibitors, and CAR-T cell therapy. Immunotherapy is a rapidly growing area of research in oncology and autoimmune diseases. Browse our peer-reviewed product directory to find the best immunotherapy tools, compare products, check reviews, and get pricing directly from manufacturers.