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A Rapid and Effective Tool for Monitoring Monoclonal Antibody Production

MedMira Inc.
13 Aug 2014

Testing of third-party monoclonal antibodies can be laborious and time consuming. In this poster, presented at AACC 2014, the authors introduce an alternative method using MedMira’s MiriadTM RVF Toolkit to quickly assess the suitability of hybridoma bioreactor supernatants.

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Miriad RVF Toolkit

MedMira Inc.

Designed with the researcher in mind, our Miriad product line opens up a world of possibility. It significantly improves the development flow from research lab concept to commercial product using our patented Rapid Vertical Flow Technology platform. Miriad RVF Toolkit facilitates the development and commercialization of rapid diagnostics. Employing MedMira Rapid Vertical Flow Technology, the Toolkit contains components to create a rapid test. The researcher need only provide the capture antigen of interest and the specimen containing the antibody. The Toolkit is an off-the-shelf set of components proven to work togetherenabling the researcher to focus on the development work instead of sourcing components.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.

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A Rapid and Effective Tool for Monitoring Monoclonal Antibody Production