ResourceSeparations

A Quick Study ‐ Comparison of Chromatography Normal Phase vs. Flash on the Gilson PLC 2020

21 Mar 2012

This application note provides a quick comparison of three pharmaceutical compounds using high pressure normal phase and low pressure flash chromatography. Comparison of peak shape, peak retention time, chromatography run time, fraction volume, and solvent consumption were all studied to determine the most efficient and optimal chromatography method.

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Flash ChromatographyFlash chromatography is a fast-preparative column chromatography technique used for separation and purification of liquid analytes. Flash chromatography systems use small silica gel particles for separation and a pressurized gas for driving the solvent through the column or pre-packed cartridge. Find the best flash chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Preparative ChromatographyPreparative chromatography equipment is used for purification purposes, separating and collecting compounds eluted from a mixture which can then be subsequently used for further purposes. This can be done in large quantities or small. Preparative chromatography systems are usually low to medium pressure liquid chromatographs that are semi-automated. Explore a range of preparative columns and fraction collectors. Find the best preparative chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Normal Phase Chromatography
A Quick Study ‐ Comparison of Chromatography Normal Phase vs. Flash on the Gilson PLC 2020