ResourceLife Sciences
A Novel Platform for Automated Production and Screening of Scaffold-Free, Organotypic Microtissues
30 Jan 2015Although the advantages of organotypic 3D-cell-culture models have been known for years, complex production and readout processes impeded its industrial implementation. This study presents a novel high throughput-compatible 96-well platform to produce organotypic, scaffold-free microtissues and its implementation in an automated screening process. This technology allows the production of tumor and primary microtissues in a hanging-drop culture by liquid top-loading similar to standard 96-well monolayer plates.
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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microtissue