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A guide to efficient and greener cannabinoid purification

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Discover the inherent benefits of centrifugal partition chromatography for cannabinoid research and production

25 Oct 2021

Chromatography technologies never stand still, and the leading purveyors of separation techniques are continually innovating in this space. Driven by the ever-growing demands from industry for precision, speed, economy, and increasingly sustainable approaches, manufacturers are now looking beyond classical liquid chromatography techniques to support scalable research and production with a focus on reducing chemical waste.

Centrifugal partition chromatography (CPC) is one technique that promises real solutions which can serve the needs of laboratory and small-scale development work through to the bioprocessing of end products at full industrial scale. In this eBook, we look at several applications of CPC solutions from Gilson to help you understand the versatility and benefits of this technology. Learn from experts how CPC works and how it can be harnessed in the high-throughput purification of multiple cannabinoids.

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VERITY CPC Pilot System

Gilson, Inc.

The VERITY® CPC Pilot System combines the PLC 2500 Purification System with a VERITY CPC 1000 PRO for high-level target compound purification. This automated, cost-effective, liquid-liquid purification technique utilizes reusable, silica-free chromatographic columns to streamline your workflow and allows you to quickly isolate specific molecules with high yields and purity. 

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VERITY CPC Lab System

Gilson, Inc.

The VERITY® CPC Lab System combines a PLC Purification System with a centrifugal partition chromatography (CPC) system for high-level target compound purification. This automated, cost-effective, liquid-liquid purification technique utilizes reusable, silica-free chromatographic columns to streamline your workflow and allow you to quickly isolate specific molecules with high yields and purity.

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VERITY CPC Process

Gilson, Inc.

The VERITY ® CPC Process system performs silica-free chromatography for process-scale purification and extraction. It combines a newly designed rotor with a capacity range of 1 to 5 liters when combined with the VERITY ® SKID

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Preparative ChromatographyPreparative chromatography equipment is used for purification purposes, separating and collecting compounds eluted from a mixture which can then be subsequently used for further purposes. This can be done in large quantities or small. Preparative chromatography systems are usually low to medium pressure liquid chromatographs that are semi-automated. Explore a range of preparative columns and fraction collectors. Find the best preparative chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chromatography Method DevelopmentChromatography method development is the process of designing and optimizing chromatographic techniques to separate and analyze complex mixtures. This includes selecting appropriate stationary and mobile phases, determining flow rates, and optimizing detection methods. Successful method development is essential for high-quality results in fields like pharmaceuticals, food safety, and environmental analysis. Explore chromatography method development tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.CannabinoidsCannabinoids are compounds found in cannabis that have therapeutic effects, such as pain relief, anti-inflammatory properties, and potential neuroprotective benefits. Research into cannabinoids is growing, particularly in the fields of pain management, neurological diseases, and cancer treatments. Browse our peer-reviewed product directory to find the best cannabinoid research tools, compare products, check reviews, and get pricing directly from manufacturers.Cannabis

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