ResourceSpectroscopy
A comprehensive method for the analysis of pain management drugs
4 Apr 2023In this application note from Waters Corporation, discover a complete method for the solid phase extraction and UPLC-MS/MS analysis of pain management drugs and drugs of abuse for clinical research. This method optimizes sample preparation to efficiently extract all analytes with a simplified procedure that reduces the number of manual steps. Furthermore, the water wettable nature of the sorbent enables in-well sample pretreatment and direct loading without conditioning and equilibration, eliminating sample transfer and potential transcription errors.
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.