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A comprehensive guide to maintaining phenotypic consistency with automated stem cell isolation and imaging

SelectScience
1 Oct 2023
Front cover and first page preview of the automated stem cell isolation and picking guide

Stem cells can self-renew and differentiate into a vast array of specialized cell types and are therefore of high value as a research model for studying development and disease. Despite their promise, stem cell workflows are inherently complex in part due to their sensitivity to environmental stress which can cause spontaneous differentiation. Additionally, the lack of standardized protocols in stem cell workflows can lead to inconsistent results.

This eBook provides a comprehensive collection of articles and interviews about the unique challenges scientists face with stem cell workflows and the benefits of automated solutions for stem cell imaging, isolation, and retrieval.

Download this free guide to learn more about:

  • The challenges of stem cell research
  • The benefits of single-cell isolation versus cell population studies
  • Fully automated image-based single-cell and colony picking for stem cells
  • Precise transfer of stem cell clones and colonies
  • Induced pluripotent stem cell (iPSC) culture, maintenance, and characterization
  • Quantitative live-cell analysis for optimization of culture conditions and evaluation of cell health in hiPSC-derived neurons

Related products

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CellCelector Flex

Sartorius Group

Fully automated cell imaging and picking system developed for the screening, detection, selection and isolation of single cells, clusters, spheroids and organoids, as well as single cell clones and adherent colonies.

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Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.Stem Cell ResearchStem cells have the ability to produce identical daughter cells as well as progeny, which commit and differentiate. Stem cell research has exciting prospects of biomedical applications in cellular disease modeling, pharmaceutical screening, and regenerative medicine.

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A comprehensive guide to maintaining phenotypic consistency with automated stem cell isolation and imaging