3 simple and proven automation protocols for serial dilution

19 Aug 2024

A serial dilution is the step-wise reduction of a concentration using a constant dilution factor and similar volumes. This highly standardized procedure has applications in drug discovery, microbiology, and molecular biology.

In this application note, INTEGRA discusses how to perform serial dilutions with optimized liquid handling parameters to prevent common issues leading to accumulated errors during inter-dependent steps.

VOYAGER Adjustable Tip Spacing Pipettes

INTEGRA Biosciences

The VOYAGER electronic pipettes enable users to change the tip spacing electronically with the push of a button. Up to three different tip spacings from 4.5 mm to 33 mm can be set and saved. Accelerate reformatting of plates, e.g. 96 well plates to 384 well plates, transfers from racked tubes into microplates or filling pockets of Agarose gels. The VOYAGER electronic pipettes feature a colour display and an intuitive touch wheel user interface. This enables quickest volume changes and easy, ergonomic modification of pipetting parameters. Ten predefined protocols are available, such as Repeat Dispense, Serial Dilute, Sample Mix. In addition, up to 20 customized protocols can be created and stored on the pipette. VOYAGER Adjustable Tip Spacing Pipette Features & Benefits:  Electronically adjustable tip spacing accelerates plate reformatting and sample transfers between different lab ware formats. Unique tip fitting design ensures that tips snap into place and will not accidently fall off. GripTips attach the same way each and every time to enable precise touching off. Intuitive touch wheel interface for rapid volume setting and easy programming. Available Models: 4-channel 6-channel 8-channel 12-channel

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Pipettes and DispensersPipettes and dispensers are essential lab equipment used to dispense measured volumes of liquid accurately. Explore a range of manual and electronic pipettes, including single and multichannel, serological and volumetric pipettes, as well as a range of pipette tips. Bottle-top dispensers are also available for simple and fast solvent dispensing. Find the best pipettes & dispensers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Liquid HandlingLiquid handling involves the precise transfer, mixing, and dispensing of liquids in laboratory settings. It is essential for accurate and consistent results in biological, chemical, and pharmaceutical research. Automated liquid handling systems improve efficiency and reduce human error in sample preparation and analysis. Explore liquid handling tools in our peer-reviewed product directory; compare products, read customer reviews, and get pricing directly from manufacturers.
3 simple and proven automation protocols for serial dilution