Next Generation Sequencing Products & Reviews

Twist's RNA Sequencing Solutions provide comprehensive next-generation sequencing (NGS) workflows, offering both targeted and whole transcriptome approaches to generate uniform, high-quality RNA sequencing libraries from diverse sample types.

The Twist RNA Exome offers a comprehensive solution for capturing human protein-coding regions, enabling efficient transcriptome analysis, isoform study, and fusion detection with high sensitivity and specificity.

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

The Twist Bioscience MRD Rapid 500 Panel is a scalable target enrichment solution for monitoring minimal residual disease that leverages Twist’s silicon based DNA synthesis platform to design and manufacture capture panels for personalized medicine. 

The Twist UMI Adapter System enhances the detection of low-frequency somatic variants in cell-free DNA (cfDNA) by incorporating unique molecular identifiers (UMIs) during library preparation, increasing sensitivity and reducing PCR errors.

Clean up and size selection of DNA and RNA for NGS workflows using magnetic beads

Removal of unincorporated terminators from sequencing reactions using magnetic beads

BioIVT provides isolated exosomes from a variety of human, animal, and plant sources, as well as custom characterization and in vitro assays investigating function and potential therapeutic benefit.

As our latest generation of RNA library preparation kits, KAPA RNA HyperPrep Kits utilize a novel chemistry and combines enzymatic steps to achieve fewer reaction purifications and yield high-quality RNA-seq libraries in a single day. They also offer flexible workflow options that include the enrichment of desired transcripts by selective mRNA capture or rRNA depletion.

Sapio LIMS is a configurable, open, and easy-to-use LIMS platform. It supports the entire laboratory workflow, from request to sample preparation to analysis and reporting. Sapio LIMS has powerful no-code configuration, making it easy to set up to support your laboratory’s unique requirements. And with a range of out-of-the-box applications, such as NGS and in vivo, you can quickly start making the most of Sapio LIMS.

Massively parallel barcoding technology enables you to easily scale up to 500,000 cells in a single experiment.

Efficient, and uniform hybridization-based capture for Whole Exome Sequencing Combining more than a decade of probe-design experience with an improved probe-manufacturing process, the new KAPA HyperExome probe pools enable efficient, uniform hybridization-based capture for Whole Exome Sequencing (WES).

The power of Fontus™ automation. Making waves in NGS library prep.

Revvity Ultrarapid Whole Genome Sequencing: Get a final report for urWGS in just 5 days!

KAPA HyperPETE (Primer Extension Target Enrichment) is a novel hybridization capture technology designed to employ primer extension reactions to specifically capture and release target library molecules for sequencing.

KAPA EvoPlus V2 Kits is an enhanced enzymatic DNA library preparation solution that features improved fragmentation performance, insensitivity to inhibitors, increased conversion efficiency & fewer sequencing artifacts.

Amplify a CRISPR guide sequence derived from a CROP-style vector alongside your standard RNA Sequencing Library.

Achieve high-performing NGS library preparation from mechanically fragmented DNA or cell-free DNA (cfDNA) in a streamlined, automation-friendly workflow with KAPA EvoPrep Kit. The KAPA EvoPrep workflow reduces pipetting and reagent preparation steps and is validated with challenging sample inputs such as cfDNA and FFPET DNA.

The Shasta Single Cell System is a state-of-the-art, automated dispensing and imaging platform for single-cell biomarker discovery, surpassing the boundaries of existing methods. and enabling the detection of more biomarkers—splicing isoforms, gene fusions, and CNVs—in more cells than ever before.

KAPA HiFi DNA Polymerase is a novel, single-enzyme system that exhibits industry-leading performance when compared with other high-fidelity polymerases and polymerase blends.

The AAVX and AAV9 Total Capsid Quantification Kits extend the Amperia™ Protein Quantification System for streamlined measurement of adeno-associated virus (AAV) vectors. Incorporating CaptureSelect™ affinity reagents from Thermo Fisher Scientific, the kits provide robust, reproducible assays for both broad serotype coverage and AAV9-specific quantification.

The Protein A and Protein G Quantification Kits extend the Amperia™ Protein Quantification System for streamlined measurement of antibodies across subclasses and species. Using Fc capture with an inverse-occupancy format, the kits deliver reproducible titres directly from crude or clarified samples, with up to 320 tests per kit.

DeNovoX software automates and accelerates sequencing, returning results equal to or better than those formerly achieved through expert manual sequencing of peptides within proteins and is ideally suited for high-throughput analyses of peptide mixtures. Product detail: DeNovoX is a fully-automated de novo sequencing software program that is capable of determining complete or partial amino acid sequences of unknown peptide…