RNA Interference Products & Reviews

The CellTag™ 700 Stain ICW (In-Cell Western™) Kits provide detection reagents for cell-based In-Cell Western Assays.

The QuantiFluor™ RNA System contains a fluorescent RNA-binding dye that enables sensitive quantitation of small amounts of RNA in solution. Detecting and quantitating small amounts of RNA is a very important step used in many biological applications, particularly in molecular biology techniques. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot anal…

High productivityVersatile: efficient in both HEK 293 & CHO synthetic mediaComplies with new regulatory requirements for large scale production

Efficient siRNA or microRNA transfection. To attain efficient and reliable siRNA or microRNA transfection, we offer DharmaFECT transfection reagents. Thermo Scientific DharmaFECT 1 is our most all-purpose transfection reagent formulation; demonstrating efficient, low-toxicity delivery to over 35 cell types. DharmaFECT 1 achieves effective transfection of siRNA and microRNA reagents at low concentrations and with low cytotoxic…

With over 20 million pre-made clones representing nearly every known gene for most common organisms, Source BioScience are your perfect partner for quick and easy solutions for gene and protein expression research. Source BioScience customers can choose from individual pre-made clones or entire clone libraries from many of the most well-known and cited clone consortia and research groups for mammalian and non-mammalian specie…

Lullaby® - siRNA transfection reagent is the ideal reagent dedicated to the transfection of siRNA. Based on an innovative technology, this new lipid-based reagent achieves extremely efficient siRNA delivery into cells. Lullaby® - siRNA transfection reagent protects siRNA from extracellular degradation and has an outstanding capacity to destabilize cells membrane, allowing delivery of important siRNA amounts into the cytosol. T…

Protein Analysis Software - the Next GenerationCLC Protein Workbench creates a software environment enabling users to make a large number of advanced protein sequence analyses, combined with smooth data management, and excellent graphical viewing and output options. Protein Workbench sets new standards for bioinformatics software with its overall graphical display, usability driven and user-friendly interface, while featuring…

Free Bioinformatics Software Not a demo. Not scaled down. No spyware. No need to register. Yet still a wide variety of features available - and - free! CLC Free Workbench creates a software environment enabling users to make a large number of bioinformatics analyses, combined with smooth data management, and excellent graphical viewing and output options. Some of the many bioinformatics analyses: • Interactive restriction site…

The New Standard for Desktop-Based Bioinformatics Tools CLC DNA Workbench provides a software environment which enables users to perform advanced DNA sequence analyses such as assembly of DNA sequence data, graphically and algorithmically advanced primer design, while offering user-friendly molecular cloning tools. CLC DNA Workbench is a bioinformatics software package containing a range of specialized DNA analyses and bioinfo…

Peroxidase labelling of proteins or amine compounds.  Only 3 hours to get conjugates, all processes in a single filtration tube, high recovery of conjugates.

Cellecta’s 80K Single-module Human Genome-Wide CRISPR Library was designed to be small enough (~80,000 constructs) to enable convenient genome-wide “dropout viability” screens with most standard human cell modules. With 4 sgRNAs targeting each gene, all of which have been designed using the latest criteria for effective guides described by Doench, et al. and containing the Cellecta-designed HEAT sgRNA structure which we hav…

Independent of your genes of interest, thes easy RNA in situ hybridization assays use common reagents and protocols; providing universal assay conditions. All RNA-ISH kits contain reagents in a convenient ready-to-use (RTU) format, and chromogenic dyes are available to interrogate a single or two genes simultaneously. Most versatile are the RNAscope Multiplex Fluorescent Reagent Kits, enabling you to interrogate 1, 2 or 3 gen…

The trusted, simple, broad-spectrum transfection reagent for most cell lines

Saturn-2D™ REDOX with CinC™ technology perfectly illustrates changes within the complex redox interaction network. Due to specially designed Cys-interacting compounds (CinC) differences in the redox status can be easily displayed, leading to dramatic time savings for further mass spec analysis. All kits are ready to use.   Experience unmatched performace of novel S-Dyes   Run 2D gels with as little sample a…

siRNA designed and modified for greater specificity

Gene silencing in difficult-to-transfect cells guaranteed

High-confidence gene silencing

Tailored transfection reagents for a wide variety of RNA and cells. High-efficiency delivery, low cellular toxicity, broad dynamic range

Crucial to any gene silencing or microRNA modulation experiment.  RNAi controls allow accurate interpretation for reliable, reproducible results.

Successful gene silencing in your cells of interest

Tightly controlled gene silencing with the most advanced and flexible single-vector inducible shRNA.

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee. NM_005194 - human NM_024125 - rat NM_009883 - mouse

DsiRNAs are 27mer duplex RNAs that demonstrate increased potency in RNA interference compared to traditional, 21mer siRNAs. Proprietary design rules produce optimized DsiRNAs that are available only from IDT.

Antisense oligonucleotides (ASOs) are short oligonucleotides that localize to the nucleus and provide a pathway for gene silencing by the RNase H pathway. Phosphorothioate (PS) linkages are available to confer nuclease resistance and, therefore, enhance intracellular stability.