Protein Quantification Products & Reviews

Recombinant monoclonal antibody to Human VEGF is an angiogenesis inhibitor, a drug that slows the growth of new blood vessels. It is licensed to treat various cancers, including colorectal, lung, breast (outside the USA), glioblastoma (USA only), kidney, and ovarian. Bevacizumab is a humanized monoclonal antibody that inhibits angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A).

Recombinant monoclonal antibody to IL5RA. It is a monoclonal antibody for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).

Recombinant Mouse Antibody (M75) is capable of binding to CA9. The adhesion site of CA IX appears to overlap with the PGEEDLP epitope of the monoclonal antibody M75, since the antibody blocks attachment of cells to immobilized CA IX protein.

Recombinant monoclonal antibody to CD274. This antibody is a human IgG1 monoclonal antibody that targets and binds to PD-L1, a protein that is often overexpressed on the surface of cancer cells and immune cells in the tumor microenvironment.

Recombinant monoclonal antibody to Human IL5. It is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5) and is used to treat certain kinds of asthma and white blood cell diseases. Recent studies have concluded that mepolizumab may improve exacerbations in patients with severe eosinophilic asthma, an adult-onset asthma that represents less than 5% of all asthma.

Recombinant monoclonal antibody to Human EGFR. Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1, and HER1 in humans).

This product is a recombinant Human antibody that recognizes MS4A1/CD20. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.

This product is a recombinant Mouse antibody that recognizes DOTA. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.

Recombinant Rabbit Antibody is capable of binding to Hypusine, expressed in Chinese Hamster Ovary cells (CHO).

Recombinant Human Antibody (B20-4) is capable of binding to VEGF, expressed in HEK293 cells. Expressed as the combination of a heavy chain (HC) containing VH from antiVEGF mAb and the CH1-3 region of human IgG1 and a light chain (LC) encoding VL from antiVEGF mAb and CL of human kappa light chain. Exists as a disulfide-linked dimer of the HC and LC heterodimer under non-reducing conditions.

Highly sensitive, fluorescence-based quantitation of purified proteins.

At-line analysis for cell culture media

For low-volume measurements

Proteins purified from their natural, endogenous sources, preserving post-translational modifications and complex native structures for biologically relevant research applications.

Easily label SNAP-tag®, CLIP-tag™, HaloTag®, or other ligands with fluorescent dyes, no purification needed. Cell membrane-permeant and impermeant dye options for intracellular or surface targets.

Our Protein Binding Platform assesses drug-protein interactions using equilibrium dialysis and ultracentrifugation methods to determine unbound fractions and distribution in biological samples including plasma, blood, tissues, and cells. This essential ADME service evaluates reversible drug transfer between compartments, providing insights into pharmacokinetics, bioavailability, and potential interactions.

Label 5-50 ug of VHH (also known as Nanobodies®) containing a single free cysteine with Biotium’s bright and photostable CF® Dyes, with no purification after labeling.

Stable Isotopes for Biomolecular NMR

SignalChem(part of Sino Biological) offers one of the most comprehensive ranges of biologically active recombinant enzymes as well as a broad range of high-quality, low-cost enzyme activators and inhibitors of different classes of enzymes including protein kinases, phosphatases, and epigenetic enzymes.

Label your IgG antibody with one of our superior CF® Dyes in as little as 15 minutes without a purification step. Labeling tolerates many common buffer components including BSA and ascites.

Complete PAGE protein analysis system

KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.

A suite of analytical services, including SPR, BLI, and ITC, to quantitatively characterize the binding kinetics, affinity, and thermodynamics of biomolecular interactions.

Label your IgM antibody with one of our superior CF® Dyes in 15-30 minutes without a purification step.

Custom chemical conjugation of Polyethylene Glycol (PEG) polymers to proteins to enhance their pharmacokinetic properties, including increased half-life and reduced immunogenicity.