Enzymes Enzyme Inhibitors Products & Reviews

NF-?B Pathway Inhibitor; Stabilizes I?B

Epigenetic modifier; Inhibits histone deacetylase (HDAC) 6

Src family kinases inhibitor; Inhibits Src, LCK, Yes, Cdc2, EGFR, VEGFR, v-Abl, and FAK

Epigenetic modifier; Inhibits histone methyltransferases SU(VAR)3-9

WNT pathway activator; Inhibits GSK3

Notch pathway inhibitor; Inhibits Notch receptor and amyloid precursor protein

p53 Inhibitor

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits CK1, ALK5 and p38 MAPK

MEK/ERK pathway inhibitor; Inhibits B­RAF V600E

Notch pathway inhibitor; Inhibits ?-secretase

Tyrosine kinase inhibitor; Inhibits ABL, SRC, LCK and YES

Notch pathway inhibitor; Inhibits ?-secretase

Inhibits EGFR and VEGFR

Activin/Nodal/TGFß pathway inhibitor; Inhibits ALK2

BMP and AMPK pathway inhibitor; Inhibits ALK2, ALK3, ALK6, and AMPK

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

Adenosine deaminase and PDE2 inhibitor

mTOR pathway inhibitor; Inhibits FKBP-12

Epigenetic modifier; Inhibits SIRT1 histone deacetylase

RHO/ROCK pathway inhibitor; Inhibits ROCK2

Calcineurin/NFAT pathway inhibitor; Binds FKBP-12

Serotonin reuptake inhibitor

Epigenetic modifier; Inhibits histone acetyltransferases (HATs) p300 and pCAF

PI3K/AKT pathway inhibitor; Inhibits Class I PI3Ks

Tyrosine kinase inhibitor; Inhibits EGFR