LC-MS Products & Reviews

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

Transforming medicine with metabolomics

Decoding lipid-driven biology

Efficient workflows for busy laboratories

Metabolomics in nutrition, microbiome, and disease

The Finnigan TSQ Quantum Series of mass spectrometers are the most advanced and powerful triple quadrupole mass spectrometers available. The Quantum Series mass spectrometers feature the patented HyperQuad™ mass analyzer technology, a rugged orthogonal source, and a completely redesigned analyzer geometry for maximum sensitivity, precision, and reliability. The Quantum Series triple quads are the only commercial triple quads a…

SEQUEST Cluster is a complete, preconfigured proteomics solution that enables accelerated throughput of increasingly complex, multidimensional informatics.Product detail:The SEQUEST Cluster offers a scalable solution for computing the large volumes of data typical in most proteomics analyses using LC/MS. Protein database search times are dramatically reduced by harnessing the power of several processing units in one, increasin…

The Finnigan LTQ high-performance 2-Dimensional Ion Trap Animations mass spectrometer redefines performance for metabolic and proteomics analyses. Product detail: Finnigan LTQ LC/MSn The Finnigan LTQ linear ion trap mass spectrometer represents a leap in LC/MSn ion trap performance. Combining patented technology from the field-proven LCQ series with advanced designs in linear trap, ion source, optics, and detector techno…

The Waters Regulated Bioanalysis Platform Solution with UNIFI®is a single-vendor solution for bioanalytical laboratories to generate quantitative results while maintaining optimal productivity, quality and consistency to maximize up-time and cost per sample.The UNIFI Scientific Information System is designed to accelerate your capabilities and anticipate your imperatives. The platform enhances your ability to develop robust m…

Enzymatic digestion of proteins in polyacrylamide gel slices and subsequent analysis of the peptides by mass spectrometry has become a routine procedure in protein analysis. In solution digestion protocols for bottom-up proteomics complement it. The DigestPro MSi automates all those procedures to achieve high throughput under controlled and reproducible conditions.

PHOTONIS Channeltron detectors provide the highest sensitivity due to superior signal collection and noise reduction, effectively improving the efficiency of your mass spectrometer. With over 150 replacement detectors to choose from, we can supply the replacement detector in a wide range of mass spectrometers, even if the instrument is no longer manufactured. Additionally, many of our detectors can be bought as complete repl…

PHOTONIS’ Advanced Performance Detectors (APDs) are plug-and-play electo-optic assemblies which provide a complete housing, facilitating manufacturing assembly, repair or replacement to mass spectrometers and other machines. Available for new machines or as replacement cartridges for existing models, over 200 types, with cartridge-mounted MCP, further simplifying additional repairs. ¶PHOTONIS Advanced Performance Detectors (AP…

PHOTONIS offers the widest and most technologically advanced variety of Time-of-Flight Detectors available. These patented detectors offer previously unobtainable levels of temporal resolution, dynamic range, and high mass detection sensitivity for TOF Mass Spectrometry. PHOTONIS' unique 2-Micron pore MCP provide the highest channel density of any MCP providing gains in excess of 5x106. PHOTONIS manufactures Time-of-Flight Det…

PHOTONIS is the industry leader in technology advancements for Microchannel Plates (MCPs). We offer a broad range of sizes, shapes and options to support a number of imaging applications. Our expertise across two production locations ensures continual research and development while ensuring our customers receive the customization and service for which we are known. For over thirty years, PHOTONIS has consistently set the stand…

The Finnigan vMALDI Ion Source system provides fast, automated MS and Data Dependent MS/MS analysis of digested protein mixtures in a single, rapid experiment. While LC/MS analysis times are typically 30 to 60 minutes, using the Finnigan LTQ with the vMALDI ion source generally requires less than a minute per sample enabling high throughput protein identification. Production: The Finnigan vMALDI Ion Source Thermo's new F…

With unparalled sensitivity and completely integrated hardware, software and methods, the system delivers an extremely powerful solution for identifying proteins from complex matrices, determining the location(s) of many post translational modifications (PTMs) and even de novo sequencing.    Product detail: Realizing that generating spectra by itself was not enough, the ProteomeX LTQ system was created with the following…

Mass Spectrometry Software for Spectral Interpretation and Component Characterization

SelexION differential mobility spectrometry is an effective ion mobility spectrometry tool for improving data quality in the quantitation and characterization of challenging samples requiring advanced analytical selectivity. SelexION on the SCIEX 5500+ series and 6500+ series delivers a new dimension of selectivity and performance for applications requiring the separation of isobaric species, elimination of challenging co-elut…

The NEW Finnigan TSQ Quantum Discovery MAX: Extraordinary Value The high-performance, ultra compact benchtop Finnigan TSQ Quantum Discovery MAX incorporates innovative new technology for increased sensitivity, precision, ruggedness, and reliability. It is principally designed for high-productivity environments such as environmental, clinical and drug discovery laboratories. With the Ion Max source, the Finnigan TSQ Quantum Di…

The cartridge-based EXP® Analytical Column System is designed for superior chromatographic analysis with each injection rated for routine use up to 20,000 psi.The new EXP® Analytical Column Holders incorporate Free-Turn® architecture allowing the user to quickly exchange columns, by hand, without breaking any fluid connections. The EXP® Analytical Column Holders are available in two formats: In-Line and Direct Connect, allowin…

With the addition of the highly flexible and versatile 3100 Mass Detector, Hitachi’s LaChrom Elite ® HPLC System further solidifies its position as the leader in chromatographic analysis for a wide range of applications. The LaChrom Elite® HPLC system, in combination with the Waters® 3100 Mass Detector, provides unmatched selectivity, sensitivity and throughput for improved laboratory productivity. Features Seamless inte…

You expect the fullest possible insight into your sample. compact delivers the highest quality of results without compromise. All specified performance parameters simultaneously delivered in a single run with no need for tuning or optimization is what makes compact unique. Full Sensitivity Resolution Having to choose between resolution and sensitivity on other instruments restricts depth to which you can understand your sample…

The EXP Ti-lok Fitting features a two-stage locking mechanism ideal for PEEK-clad or sleeved fused silica, such as PEEKsil™ tubing. The two-stage fitting features a patented auto-adjusting titanium hybrid ferrule that seats in any port. The titanium collet locking mechanism provides a second grip point to even the pressure load over the tubing and not crush the silica. The incorporated rear collet locking mechanism is not remo…

BiopharmaLynx™ automates the processing and interpretation of biopharmaceutical product LC/MS data, enabling you to characterize your products. Developed with biopharmaceutical thought leaders for confident characterization and optimized workflow, BiopharmaLynx™ leverages Waters' leading protein informatics expertise. Determine the identity, purity and stability of biopharmaceuticals, working with either peptide maps or intac…

The only comprehensive screening solution The Waters® Screening Platform Solution with UNIFI™ is the first and only comprehensive screening solution – target, identify, quantify, and review using a streamlined analytical workflow that enables more accurate results across a wide range of applications.The platform is holistically designed, combining world-class instruments, software, Waters’ Analytical Standards and Reagents, a…