Recombinant Cynomolgus Interferon Alpha 2 (Ile 16) Catalog Number: 16100-1 Source: E. Coli Accession Number: N/ASize: 1 x 105 units Purity: ≥ 98% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1/2007): $280
Recombinant Pig IFN Alpha Catalog Number: 17100-1 Activity: 3.8 x 107 u/mg Source: E. Coli Accession Number: NM_021068 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I InterferonShipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1/2007): $270
Recombinant Ovine IFN Tau. Active on sheep, cow, human and mouse cells. Catalog Number: 18610-1 Activity: 5.7 x 107 u/mg Source: E. Coli Accession Number: X56341 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1/2007)…
Recombinant Bovine IFN Tau. Active on cow, sheep, human and mouse cells. Catalog Number: 19610-1 Activity: 4.8 x 107 u/mg Source: E. Coli Accession Number: M13557 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, InterferonShipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt
Quantitative determination of Hu-IFN alpha bioactivity Sample Volume: 25 µl Catalog Number: 51100-1 Quantity: 1 x 96 Assay Range: 1.5-200 IU/ml Shipping Conditions: Dry ice Storage temp.: -80˚C Shelf Life: 9 months from date of manufacture 2007 Retail Price: $895
ADP detection with HTRF® quality.The HTRF® Transcreener™ ADP assay is a homogeneous non-radioactive assay which measures the generation of ADP. This universal solution can be used to assess kinase and ATPase activity for High Throughput Screening and profiling applications. Enzyme-free detection allows for a low false positive rate. ADP is directly detected by a monoclonal antibody labeled with Eu3+ cryptate and correlates tig…
In 2008 Gentronix launches a new S9 protocol to extend the application of the GreenScreen HC assay to include the detection of genotoxic metabolites. Many pharmaceuticals only present a genotoxicity hazard after metabolism and such chemicals are called pro-mutagens or pro-genotoxins. Generally, although not exclusively, the liver is considered responsible for the “metabolic activation” (MA) of promutagens. However, none of t…
Cisbio offers a line of three ready-to-use assays for measuring cAMP using HTRF® technology. Each kit is optimized for detecting a specific range of cAMP concentrations to allow fine tuning of assay sensitivity. These kits enable high quality, cell-based assay screening in 96-, 384- or 1536-well formats.
Cisbio's cAMP HiRange kit is designed to address either the use of cell-based and cellular membranes-assays in GPCR activation and Adenylate Cyclase activity screening. The cAMP HiRange assay is highly robust and produces quality results while eliminating the need for a continuous supply of living cells.
IP1, a downstream metabolite of IP3, accumulates in cells following Gq recepetor activation and is stable in the presence of LiCl making it an ideal GPCR (Gq) functional assay. Cisbio developed and patented a highly accurate HTRF assay for measuring IP1 in 96-, 384- and 1536-well formats providing for a HTS compatible assay.
Cyclic GMP (Guanosine 3',5'-cyclic monophosphate) is a major second messenger that mediates cell activities by activating protein effectors such as protein kinase G (PKG), cGMP-regulated phosphodiesterases (PDEs), and cGMP-gated channels. Cellular cGMP is synthesized by soluble Guanylyl Cyclases and particulate Guanylyl cyclase, triggered by nitric oxide and atrial natriuretic peptide (ANP) binding respectively. Key processes…
Stable, recombinant AequoScreen ® parental cell line expressing aequorin and Gα16 in CHO-K1 host cells.
An acetyl-biotinylated substrate recognized by a Eu3+ anti-acetyl MAb and SA-XL665, which is used in activator screening or to test an High Throughput SIRT1 inhibitor. The level of enzymatic activity is inversely proportional to the amount of signal produced in the system. For more information please visit Cisbio Bioassays website.
In order to provide you with the most advanced tools for GPCR cell-based assays HTRF Technology now incorporates Lumi4®-Tb chemistry. Lumi4®-Tb is the first and only TR-FRET terbium cryptate, and is fully compatible with all existing HTRF readers. Therefore IP-One Tb offers new levels of sensitivity and performance in cell-based assays.
A novel thermoreversible gel mountant for extended immobilization and imaging.
Cisbio Bioassays's cAMP HiRange kit is designed to address either the use of cell-based and cellular membranes-assays in GPCR activation and Adenylate Cyclase activity screening. The cAMP HiRange assay is highly robust and produces quality results while eliminating the need for a continuous supply of living cells. Features: Simple and rapid assay protocol Small quantity of membrane required per assay Signal to background ratio…
R&D Flow Cytometry Kit - Flow cytometry kits designed for analysis of cell populations use up to four fluorochrome-conjugated antibodies. Flow cytometry facilitates quantitative, multiparameter analysis of cell populations based on the expression of cell surface and/or intracellular molecules. R&D Systems offers a wide range of biotin-, fluorescein-, phycoerythrin-, or allophycocyanin-conjugated monoclonal antibodies specific…
R&D Prostaglandin E2 Parameter ELISA Kit - For the quantitative determination of Prostaglandin E2 (PGE2) in cell culture supernates, serum, plasma, and urine. The R&D Parameter PGE2 ELISA is a 3.5 hour forward sequential competitive enzyme immunoassay designed to measure PGE2 in cell culture supernates, serum, plasma, and urine. This R&D Paramerter assay is based on the forward sequential competitive binding technique in whic…
R&D Proteome Profiler Human Phospho-Kinase Array Kit - Human Phospho-Kinase Array Kit for the parallel determination of the relative levels of protein phosphorylation. The kit contains 4 sets of 2 membranes - each spotted in duplicate with 46 different kinase antibodies. The R&D Human Phospho-Kinase Array is a rapid, sensitive, and economical tool to simultaneously detect the relative levels of phosphorylation of 46 kinase ph…
R&D VEGF -Recombinant Human VEGF 165R Protein Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. Specifications and Use for R&D VEGF 165RSource of R&D VEGF• A DNA sequence encoding the 165 amino acid residue variant of human VEGF (Leung, D.W. et al., 1989, Science 246:1306) was expressed in…
R&D Activin - Recombinant Activin A Protein from Human/Mouse/Rat Activins and inhibins, members of the TGF-β superfamily, have been shown to have a wide range of biological activities including: mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and reproductive physiology. Specifications and Use for R&D Activin ASource of R&D Activin• A DNA sequence encoding the human Activin A protein sequenc…
R&D Systems Recombinant Human BMP-4 BMP-4 is a TGF-β superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Specifications and Use of R&D BMP-4R&D BMP-4 Source • A DNA sequence encoding the human BMP-4 mature chain (amino acid r…
R&D Recombinant Mouse Wnt-3a Wnt proteins are secreted glycoproteins that contain a conserved pattern of 23-24 cysteine residues. Wnts play critical roles in both carcinogenesis and embryonic development. Specifications and Use for R&D Wnt-3aSource of R&D Wnt-3a • A DNA sequence encoding the signal peptide from human CD33, Met 1 - Ala 16, joined with the mature mouse Wnt-3A, Ser 19 - Lys 352 (Accession # P27467; Roelink, H.…
R&D Systems Recombinant Human IL-4 Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa - 18 kDa Th2 cytokine that shows pleiotropic effects during immune responses. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four α-helix structure. Specifications and Use of R&D Systems Recombinant Human IL-4Source • A DNA sequence en…
R&D TNF-alpha / TNFSF1A - Recombinant Human Protein Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. Specifications and Use for R&D TNF-alphaSource of R&D TNF• A DNA sequence encoding the mature human TNF-α protein sequence (Accession…
