Drug discovery > Target Discovery Products & Reviews

This microplate has half the growth area of a standard 96 well plate Flat bottoms with 190 µL total volume White walled plates enhance luminescent signals and have low background luminescence and fluorescence Opaque walls to prevent well-to-well crosstalk Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Bulk packed 20 per bag

Bottles are manufactured from virgin polystyrene, caps from high density polyethylene Both resins meet the USP Class VI requirements for plastic containers and closures Treated for optimal cell attachment One piece seamless construction with printed graduations Printed lot numbers to aid in product traceability Sterilized by gamma radiation and certified nonpyrogenic

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Without lids, lids supplied separately Sterilized by gamma radiation and nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 25 per bag

Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescent and enabling readings down to 340nm Designed to reduce well-to-well crosstalk during luminescent assays Can be used for both top and bottom reading instruments Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the i…

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Certified DNase- and RNase-free Total volume is 320 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately

Useful for the mechanical harvesting of cells Blade design minimizes cell damage and ensures even contact with the growth surface Designed for use in large flasks and roller bottles Individually wrapped Sterilized by gamma radiation and certified nonpyrogenic

Cisbio's HTRF® KinEASE™ platform has expanded to include a universal assay for tyrosine kinases. The HTRF KinEASE TK assay is based on our patented HTRF technology and uses a unique tyrosine peptide substrate in combination with a Europium-labeled monoclonal antibody. The HTRF KinEASE™ TK assay has been validated on 59 tyrosine kinases to-date including both receptor and cytoplasmic TKs. A proprietary substrate stabilizing buf…

CLC Combined Workbench includes all features and functions of CLC Free Workbench, CLC Protein Workbench, and CLC Gene Workbench. The program sets new standards for bioinformatics software with its overall graphical display and usability driven, user-friendly interface. In addition, it features a number of unique and innovative bioinformatics tools for supporting advanced biochemistry and molecular biology lab research. CLC Com…

CLC bio presents its new software module for Multilocus Sequence Typing (MLST). MLST is a portable and precise state-of-the-art technique for typing bacteria and yeast isolates. It is based on DNA sequence data from a number of house-keeping genes. For each gene, the experimental data is compared to a database of known alleles and a fi nal sequence type is assigned by combining information from all genes. Easy The CLC MLST Mod…

Gentronix has launched a new, accurate and fast in vitro mammalian cell genotoxicity assay - GreenScreen HC. The TK6 host cells are p53 competent and familiar to most genetic toxicology laboratories. A patented GFP reporter system exploits the proper regulation of the GADD45a gene. The assay delivers both high specificity and high sensitivity and detects all common mechanistic classes of genotoxin. The 96-well microplate for…

Demecolcine Synonyms: N-Deacetyl-N-methylcolchicine 6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)benzo[a]heptalen-9(5H)-one N-Methyl-N-desacetylcolchicine Colchamine Santavy’s substance F CAS No.: 477-30-5 Molecular formula: C21H25NO5 Physical Appearance:Slightly yellow powder Purity: >98% (sum of enantiomers by HPLC) Soluble in: acidified water, alcohol, ether, chloroform Product Description: Used to immobilize chromosome…

IP-One ELISA assay kit from Cisbio Bioassays - Simple and highly accurate measurement of IP1 IP1, a downstream metabolite of IP3, accumulates in cells following activation of Phospholipase C (PLC) coupled receptors. Among them, the Gq coupled GPCRs represent the most important family of receptors which can activate the β subtype of the PLC family. Other receptor types, like protein tyrosine kinase receptors, antigen or immuno…

The TV200 twin-plate 20.5 x 10cm (W x H) wide format mini-gel units are designed specifically for PAGE techniques requiring tape-cast gels or gels cast within the TV200-MC2 2-gel and TV200-MC10 10-gel multicasters, which are also available through Scie-Plas.A 20.5cm gel width allows the user to separate twice the number of samples within a single gel, thereby eliminating the problems borne from comparing samples resolved in 2…

The TV200Y twin-plate 20.5 x 10cm (W x H) wide format mini-gel unit includes, as standard, a precision engineered casting base, which acts in conjunction with our recently modified TV200-GRM to provide simple, leak-free casting.Twin screws, located on each gel clamp within the GRM, work in tandem with a dovetailed silicone gasket to distribute pressure evenly along the height and breadth of the gel, while glass plate stops loc…

With the all new CLC RNA Workbench, CLC bio brings you complex analysis of RNA molecules in a fully integrated, user-friendly and graphically advanced bioinformatics framework. Advanced The CLC RNA Workbench gives the user easy access to a range of complex algorithms and options. RNA secondary structures can be predicted using state-of-the-art free energy minimization algorithms and parameters, thermodynamic and statistical d…

Waters offers a broad range of vials, each one is held to tight dimensional tolerances and the certified products have cleanliness measured by LC and MS.LC/GC Certified vials are tested by LC/UV for residues of chemicals used in processing and packaging vials. The septa are tested by headspace GC to ensure low levels of low molecular weight polymer. These vials are suited for analyte concentration in the µg/mL concentration; t…

The Waters IdentityE High Definition Proteomics system defines the new standard for rigorous protein identification. The IdentityE High Definition Proteomics System is an UltraPerformance LC® (UPLC)/High-Bandwidth Mass Spectrometry (MS E) system solution suitable for confident protein identification designed to meet stringent requirements as outlined by leading scientific journals.The new Waters IdentityE High Definition Pro…

The new Guava Nexin® reagent monitors induction of apoptosis quickly and easily, with minimal chance for contamination. Annexin V is a calcium-dependent phospholipid binding protein with high affinity for phosphatidylserine (PS), a membrane component normally localized to the internal face of the cell membrane. Early in the apoptotic pathway, molecules of PS are translocated to the outer surface of the cell membrane where Ann…

Millipore's full-length mTOR kinase is now available as part of the KinaseProfiler™ Service. This kinase is the first biologically relevant mTOR to be commercially available. The KinaseProfiler Service offers 264 kinases for selectivity profiling, using a catalytic radiometric assay format. The addition of the full-length mTOR to the KinaseProfiler panel provides high-quality, confidential screening of compounds against this c…

Do you - have trouble finding an assay that fits your needs perfectly or do you want to convert your ELISA into an homogeneous method? Through Assays on demand, Cisbio gives you a list of its latest developments for the Drug Discovery field. To discover the extent of our expertise and know-how, and find a solution to your specific needs, see our service offer.These assays on demand are sold frozen and available in 1,000 and 20…

The Picovitro plates are optimal diagnostic tools for studying thousands of individual living cells in real time, applicable on both adherent and non-adherent cells for short-term (72 hours) or long-term (10-14 days) analysis. This MicroTiter plate format is available with 3243 wells. It is compatible with standard instruments, e.g., flow cytometer with sorting capabilities.

The Picovitro plates are optimal diagnostic tools for studying thousands of individual living cells in real time, applicable on both adherent and non-adherent cells for short-term (72 hours) or long-term (10-14 days) analysis. This MicroArray format is available with 672 wells. It is compatible with standard instruments, e.g., flow cytometer with sorting capabilities.

Millipore now proudly offers the MILLIPLEX® MAP Human Cancer Biomarker Panel. The Cancer Biomarker Panel includes both a Five-Plex assay, which simultaneously measures five serum biomarkers, Macrophage Migration Inhibitory Factor (MIF), Prolactin, CA-125, Leptin and Osteopontin (OPN), and a Single Plex IGF-II assay. The combination of the six serum biomarkers that discriminate between disease-free and ovarian cancer patien…

Aitken Scientific have created a software product called A-S Login (fully validated to GAMP standards) which will enable the pharmaceutical industry and its suppliers to minimise cost and time when implementing the requirements of 21 CFR Part 11.     • Maintains permitted applications, allowing versions and access rights to be controlled.     • Maintains the list of authorised users             o Password administration…

A simple 7-minute sample preparation procedure is the first part of a complete workflow provided by the TaqMan® Gene Expression Cells-to-CT™ Kit. Remove the guesswork of assembling separate RNA purification, RT, and real-time PCR kits, and achieve unsurpassed performance and sensitivity in gene expression analysis, including detection of siRNA-induced mRNA knockdown. - Complete solution—Optimized workflow includes cell lysis r…