Drug discovery > Target Discovery Products & Reviews

The LAMBDA MINIFOR bench-top laboratory fermenter and bioreactor was developed as a result of the need to construct a small laboratory fermentor for volumes from 35 ml to 6.5 liters. Based on long personal practical experience of fermentations we wanted to create a fermentor, which was easy to use and with the capacity to measure and control all the important parameters of the biological culture. The fermentor had to take up m…

Strep-Tactin Superflow combines superior mechanical stability and outstanding flow characteristics with high dynamic binding capacity. It is suitable for increased flow rates and is also useful for the purification of large protein complexes. The Strep-tag® / Strep-Tactin® purification system allows the isolation of above 95% pure and functional proteins after one chromatographical step. The Strep-tag system is based on the…

Cell biology is reliant on the investigation of unmanipulated naturally occurring cells. State-of-the-art receptor specific isolation procedures, however, leave binding reagents on the isolated cells which is likely to induce unwanted cell modifying signalling events. This can now be prevented by using a novel purification approach called Streptamer® technology. Mild purification conditions at low temperatures along with a qui…

MATra-si Reagent for efficient transfection of siRNA/miRNA as well as Antisense Oligos (ODN) using IBA's Magnet Assisted Transfection technology (MATra). MATra is a very gentle, easy-to-handle, fast and highly efficient technology to transfect cells in culture. Data from a variety of species using cell lines or primary tissue culture have accumulated including human, monkey, mouse, rat, xenopus, pig, cat or fish. Applications…

MATra-A Reagent for efficient transfection of plasmid DNA using IBA's Magnet Assisted Transfection technology (MATra). MATra is a very gentle, easy-to-handle, fast and highly efficient technology to transfect cells in culture. All types of nucleic acids from plasmid DNA or siRNA to oligonucleotides can be used with the MATra approach. Data from a variety of species using cell lines or primary tissue culture have accumulated in…

Test set for comparison of Magnet Assisted Transfection versus Magnet Assisted Lipofection. Including a one-month-rent of a universal magnet plate. Optimized for siRNA transfections. Magnet Assisted Transfection (MATra) is a new, easy-to-handle, very fast and highly efficient technology to transfect cells in culture. Data from a variety of species using cell lines or primary tissue culture have accumulated including human, mon…

The NorDiag Bullet instrument is CE IVD ready and provides TRUE walk away automated sample preparation for molecular diagnostics. The NorDiag Bullet is compact yet flexible, designed to provied targetend solutions for the user's needs.

Key Features of the cloning technology Clone any insert, at any site within any vector Restriction enzyme, phosphatase and ligase free system Powerful technology to join multiple fragments at once Rapid one reaction for 5 minutes at room temperature, then fusion on ice for 10 minutes Introduce or correct mutations at will in cDNAs Amenable to high throughput cloning applications

The BioSorter is a large particle flow cytometer designed to analyze, sort and dispense biological materials and other objects ranging in size from 10 to 1500 microns in diameter. The system is designed to handle objects which are too large or too fragile for traditional flow cytometers. Examples include small multicellular model organisms, delicate large cells / cell clusters, small seeds and beads used as microcarriers or fo…

Disposable L-Shaped Cell Spreaders The smooth surface of heathrow Scientific Disposable L-Shaped Cell Spreaders will not tear agar plate or disturb media layer. Made from ABS plastic and measuring 146 x 38 mm; 4 mm diameter. Disposable L-Shaped Cell Spreaders come sterile in a bag of 10 for immediate use without flaming.

Disposable Delta™ Cell Spreader The uniquely shaped Disposable Delta™ Cell Spreader has an innovative edgeless design—no need to worry about tearing the agar. The Heathrow Scientific Disposable Delta™ Cell Spreader has a delta-shaped head distributes pressure evenly for smooth spreading. Handle flexes slightly under pressure and is rippled for easy manipulation. Sterile ABS Disposable Delta™ Cell Spreaders are individually bag…

PHI nanoTOF TOF-SIMS The new PHI TRIFT V nanoTOF surface analysis instrument is the next generation of PHI’s highly successful line of TOF-SIMS instruments which utilize the patented TRIFT analyzer. Several significant improvements have been introduced with the nanoTOF. The superior performance TRIFT analyzer has been combined with a revolutionary new sample handling platform. This innovative new sample handling platform was…

The InviGenius provides advanced and reliable performance in automated nucleic acid sample preparation in combination with the well established magnetic bead based InviMag technology for DNA and RNA purification – especially for increased standardization and streamlined laboratory workflows. Innovative functions and optimized protocols enable reliable results of high quality. The InviGenius automated system, with built-in touc…

Functional cell-based assays provide more physiologically useful information compared to binding and non-cellular assays. ChanTest offers cell-based assays to over 90 ion channel targets for screening and profiling for both early discovery and safety liability assessment. Both replicating and division-arrested cell lines are available for most targets which have been validated on a variety of automated electrophysiology plat…

Mass Flow Controllers & Mass Flow Meters - Mass Flow Controller Products from MKS Instruments Enabling our customers to bring their products and processes to market faster, more reliably, and more cost effectively is at the heart of our mass flow controller (MFC) design philosophy. The MKS family of mass flow controller and mass flow meter instruments measure and control the flow of critical gases in a wide variety of applicat…

Flasks Nunclon™Δ Surface • Cell culture flasks with surface areas from 25-175 cm² • Filter caps or vent/close caps available for good gas exchange • Extra caps included in every carton • Short, wide neck for easy access • Individually leak tested • Excellent optical quality • Nunclon™Δ certified • Barcoded 175 cm² with large Code 128

Exiqon miRCURY LNA™ First-strand cDNA Kit First-strand cDNA synthesis reagents for high performance microRNA real-time PCR using the miRCURY LNA™ microRNA PCR system. Features of the Exiqon miRCURY LNA™ First-strand cDNA Kit: • Optimized for fast, easy and reliable first-strand cDNA synthesis using our miRCURY LNA™ microRNA PCR system • Includes a thermostable and highly reliable reverse transcriptase The miRCURY LNA™ Fir…

HENDRIX SM100 - Programmable Ultrasonic Microplate Fluid ProcessorFeatures of the HENDRIX SM100 system: • Processes 24, 96, 384, 1536 and 3456-well polypropylene, polystyrene, and COC SBS format microplates • Compact, modular design - efficient for integration/stand-alone use      - Fluid processor unit occupies about ½ sq. ft. of deck space (W: 8.25" D: 8.75" H: 4.25")      - Base control unit easily sits underneath lab bench…

Cell Membranes - Custom Preparation of Cell Membranes from CCS Cell Culture Service Preparations membranes from cell which are expressing a target receptor, transporter or ion channel at a high density are a useful tool in drug research. Embedded in a membrane fragment or vesicle the proteins remain in a functional native confirmation. Ligand binding assay and functional GTP-gammaS assays can be performed with these preparati…

Components of the Upstate (Millipore) Casein Kinase 2 Assay Kit:• Casein Kinase 2 Substrate Peptide (Cat.# 12-330) • Assay Dilution Buffer I (ADBI) (Cat.# 20-108) • PKA Inhibitor Cocktail (Cat.# 20-114) • Magnesium/ATP Cocktail (Cat.# 20-113) • P81 Phosphocellulose Squares (Cat.# 20-134) For use to measure the phosphotransferase activity of Casein Kinase 2 (CK-2) in immunoprecipitates and column fractions based on phosphorylat…

Thermo Scientific* LTQ FT Ultra combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power and versatility. Ultra-high resolution and sensitivity coupled with sub ppm mass accuracy, and MSn are universally available for the toughest applications demanding rigorous structural characterization.

HyClone Classical Liquid Media: BME/EBSS Thermo Scientific HyClone Classical Liquid Media: BME/EBSS is manufactured using ISO 9001:2000-certified processes. High yield cultures begin with high quality media. In order to maintain these standards, all HyClone products as well as raw material components must pass strict Quality Control testing to confirm the appropriate level of quality. Each raw material has a specification docu…

Features of the Drummond Scientific Nanoject II Auto-Nanoliter Injector include: • Automated Microprocessor controlled Microinjection Pipet delivering precise nanoliter volumes accurately • Remote control and nonrotating plunger eliminates vibration allowing precise injection minimizing possible cell rupture from microinjector• Selectable Injection Volumes: from 2.3 nanoliters to 69.0 nanoliters in 16 increments • Supplied wi…

The Recording Nanoject II: Enables High Precision Electrophysiological Guidance of Nanoliter Injections into the Brain Features of the Drummond Scientific Recording Nanoject II include:• Facilitates connection to an extracelluar amplifier to allow recording of neural activity • Supplements stereotaxic coordinates in guiding the placement of small injections • Provides direct displacement of neuronal tracer or excitotoxin fro…

Developed for your most demanding LC/MS/MS quantitative applications, the Quattro Premier™ XE tandem quadrupole mass spectrometer features the highest levels of sensitivity, selectivity, robustness, speed and accuracy. To maximize the analytical advantages of your ACQUITY UPLC® System, the Quattro Premier XE operates at the highest data acquisition rates. Together, the ACQUITY UPLC® System and the Quattro Premier XE give you i…