The latest development in high shear lab mixing – the new Silverson L5 Series – is ideal for all laboratory work, research and development, QA analysis and small scale production in all industries. The L5 Series Laboratory Mixer is suitable for the widest range of applications – mixing, emulsifying, homogenising, disintegrating and dissolving – with an efficiency and flexibility unmatched by other machines. With a capacity…
The large capacity SC154 Hot Block will digest up to 54, 50mL samples simultaneously in just a 15 X 21.5" footprint. Constructed of Graphite and Kydex® the corrosion-resistant SC154 was designed for environmental and other acid digestions prior to metals determinations. The SC154 uses a maximum of 1065 watts of power and will maintain sample uniformity to ±1.5°C. Heat is provided by a low-wattage heating mat that provides extr…
The NL100 Nitrogen Laser is ideal for fluorescence measurements, MALDI-TOF mass spectrometers, and other pulsed UV radiation experiments. It provides 3.5 ns pulses at 337 nm (UV), with repetition rates up to 20 Hz. The pulse energy is 170 µJ, which results in a peak power of 45 kW and an average power of 3 mW. The NL100 can be triggered internally or externally at rates up to 20 Hz. It can also provide a sync output pulse (opt…
The SNAP i.d. Protein Detection System revolutionizes the quality of your blots every time — in record time! Unlike conventional Western blotting, where diffusion is the primary means of reagent transport, the SNAP i.d. system applies a vacuum to actively drive reagents through the membrane. This novel method allows you to optimize your blotting conditions in record time for maximum results. The SNAP i.d. system minimizes over…
R&D Systems Recombinant Human BMP-4 BMP-4 is a TGF-β superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Specifications and Use of R&D BMP-4R&D BMP-4 Source • A DNA sequence encoding the human BMP-4 mature chain (amino acid r…
R&D Recombinant Mouse Wnt-3a Wnt proteins are secreted glycoproteins that contain a conserved pattern of 23-24 cysteine residues. Wnts play critical roles in both carcinogenesis and embryonic development. Specifications and Use for R&D Wnt-3aSource of R&D Wnt-3a • A DNA sequence encoding the signal peptide from human CD33, Met 1 - Ala 16, joined with the mature mouse Wnt-3A, Ser 19 - Lys 352 (Accession # P27467; Roelink, H.…
R&D Systems Recombinant Human IL-4 Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa - 18 kDa Th2 cytokine that shows pleiotropic effects during immune responses. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four α-helix structure. Specifications and Use of R&D Systems Recombinant Human IL-4Source • A DNA sequence en…
R&D TNF-alpha / TNFSF1A - Recombinant Human Protein Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. Specifications and Use for R&D TNF-alphaSource of R&D TNF• A DNA sequence encoding the mature human TNF-α protein sequence (Accession…
R&D Systems Recombinant Human FGF basic (146 aa) FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35 - 60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. Specifications and Use of R&D FGF basic Source of R&D FGF • A DNA sequenc…
R&D Systems Recombinant Human IL-6 Interleukin 6 (IL-6) is a pleiotropic α-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic Specifications and Use of R&D IL-6 Source• A DNA sequence encoding the mature human IL-6 protein sequen…
R&D GM-CSF -Recombinant Mouse Protein GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. Specifications and Use for R&D GM-CSF Source of R&D GM-CSF • A DNA…
R&D Systems Recombinant Human IGF-I/IGF-1, CF Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-I is synthesized as two precursor isoforms with N- and alternate C-terminal propeptides. These isoforms are differentially expressed by various tissues. Specifications and Use of R&D Recombinant Human IGF-1 / ICF-1, CFSource…
R&D Systems Recombinant SCF Protein Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. Specifications and Use for R&D SC…
R&D Mouse TNF-alpha/TNFSF1A DuoSet This R&D DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse Tumor Necrosis Factor alpha (TNF-alpha). DuoSets are designed for the analysis of cell culture supernates. Other sample types, such as serum and plasma, need to be validated prior to use in this R&D DuoSet. Each R&D DuoSet ELISA kit cont…
R&D SCF - Recombinant Mouse Protein Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. Specifications and Use for R&D SC…
R&D Systems Recombinant Human LDL RThe low density lipoprotein receptor (LDLR) is the founding member of the LDLR family of scavenger receptors. This family contains transmembrane molecules that are characterized by the presence of EGF repeats, complement-like repeats, and YWTD motifs that form β-propellers. Specifications and Use for R&D LDL RSource of R&D LDL R• A DNA sequence encoding the signal peptide from human CD33 was…
R&D M-CSF - Recombinant Mouse Protein M-CSF, also known as CSF-1, is the primary regulator of macrophage survival, proliferation and differentiation and is essential for the survival and proliferation of osteoclast progenitors. M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.…
R&D PDGF BB, CF - Recombinant PDGF-BB Human Protein Platelet-derived growth factor (PDGF) was discovered as a major mitogenic factor present in serum but absent from plasma. It was found to be secreted from the α-granules of platelets activated during the coagulation of blood to form serum. Specifications and Use of R&D PDGFSource of of R&D PDGF • A DNA sequence encoding the 109 amino acid residue mature human PDGF-B chain p…
The IsoPrime is a high performance gas source stable isotope ratio mass spectrometer designed to operate in dual inlet or continuous flow modes of operation. The modules are designed to handle samples such as solids, liquids or gases and prepare them to be introduced into the ion source of the IRMS as purified gases. Resultant prepared gases such as (H2, CO2, CO, N2, SO2 or N2O) are then ionised and analysed for their isotopic…
R&D Systems -  Recombinant Human Bone morphogenetic protein 2 (BMP-2) Bone morphogenetic protein 2 (BMP-2)is a member of the BMP subgroup of the TGF-β superfamily. It plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration.Specifications and Use of R&D BMP-2R&D BMP-2 Source • The DNA sequence encoding human BMP-2 (Wozney, J. et al., 1988, Science 242…
R&D Systems - Recombinant Human HGF (NS0-expressed)HGF, also known as Hepatopoietin A, was initially identified as a potent mitogen for hepatocytes in primary culture. Subsequently, HGF was also shown to be mitogenic for a variety of cell types including endothelial and epithelial cells, melanocytes, and keratinocytes. Specifications and Use of R&D HGFSource of R&D human HGF • A DNA sequence encoding the 728 amino acid residu…
R&D Systems Recombinant Human IL-1 beta/IL-1F2 IL-1 is a name that designates two pleiotropic cytokines, IL-1α (IL-1F1) and IL-1β (IL-1F2), which are the products of distinct genes. IL-1α and IL-1β are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. S…
R&D Systems Recombinant Human IL-2 Interleukin-2 (IL-2) is a O-glycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Specifications and Use of R&D IL-2 Source • A DNA sequence encoding the mature human IL-2 protein sequence (Taniguchi et al., 1983, Nature 302: 305 - 310; Ma…
R&D Systems Recombinant Human FGF basic (157 aa)FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35 - 60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. This factor contains four cysteine residues, but reduced FGF basic retains fu…
