Drug discovery > Target Discovery Products & Reviews

The XL1-Blue strains are an all-prupose line of competent cells that are ideal for routine cloning needs. 

Most E. coli hosts contain both DNA adenine methylation (dam) and DNA cytosine methylation (dcm) genes. These genes code for proteins that methylate specific sequences when DNA is propagated, making subsequent digestion with methylation-sensitive restriction enzymes impossible. Agilent offers the SCS110 and JM110 strains, which lack both dam and dcm activity. 

This collection of competent cells provides customers with classic E. coli strains that have been engineered to become competent for use in cloning experiments.

High efficiency competent cells in convenient packaging designed to satisfy higher throughput requirements. For ultimate convenience we offer custom configurations, formulations, and packaging options.

High efficiency competent cells in convenient packaging designed to satisfy higher throughput requirements. For ultimate convenience we offer custom configurations, formulations, and packaging options.

Replicating eukaryotic DNA in prokaryotic cells can be problematic. Particular eukaryotic genes may contain inverted repeats or secondary structures, such as Z-DNA, that can be rearranged or deleted by E. coli DNA repair systems. The SURE competent cells are deficient in the E. coli genes involved in the rearrangement and deletion of DNA, thus improving cloning efficiencies of DNA containing irregular structures in prokaryoti…

Replicating eukaryotic DNA in prokaryotic cells can be problematic. Particular eukaryotic genes may contain inverted repeats or secondary structures, such as Z-DNA, that can be rearranged or deleted by E. coli DNA repair systems. The SURE competent cells are deficient in the E. coli genes involved in the rearrangement and deletion of DNA, thus improving cloning efficiencies of DNA containing irregular structures in prokaryoti…

Replicating eukaryotic DNA in prokaryotic cells can be problematic. Particular eukaryotic genes may contain inverted repeats or secondary structures, such as Z-DNA, that can be rearranged or deleted by E. coli DNA repair systems. The SURE competent cells are deficient in the E. coli genes involved in the rearrangement and deletion of DNA, thus improving cloning efficiencies of DNA containing irregular structures in prokaryoti…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…

The SignalScout collection of phosphatase reagents includes the largest collection of human phosphatase expression clones and substrate trapping mutant expression clones.  Largest collection of active phosphatase enzymes, human phosphatase expression clones, and substrate trapping mutant expression clones  Purified GST-tagged active phosphatases for in vitro assay studies  Protein tyrosine, lipid, and dual specificity pho…