Drug discovery > Target Discovery Products & Reviews

Asensitive, high-throughput method for quantifying global changes in the level of specific histone modifications

Purification of core histones (H2A, H2B, H3 and H4) using very small amounts (as little as 0.9 x 105 cells) of starting material

Screen antibodies, enzymes and proteins for interations with histones and their post-translational modifications

Detect and capture DNA fragments containing 5-hydroxymethylcytosine (5-hmC) DNA methylation for analysis

Immunoprecipitate and enrich for DNA fragments containing 5-hydroxymethylcytosine (5-hmC)

Immunoprecipitate and enrich for single-stranded DNA fragments containing 5-methylcytosine (5-mC)

Fast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA

Novel technology that allows for positive identification of unmethylated DNA fragments

Reagents to measure luciferase reporter signal as part of the LightSwitch Luciferase Assay System

Comprehensive services for DNA enrichment and profiling of genomic regions marked by DNA methylation or DNA methyl variants

Fastest, most efficient methylated DNA enrichment method on the market

Comprehensive services for DNA enrichment and profiling of genomic regions marked by DNA methylation or DNA methyl variants

Transcriptome profiling by RNA-Seq

Custom cloning services to clone any fragment from the human, mouse or rat genome into any LightSwitch luciferase reporter vector

Custom site-directed mutagenesis services to create any sequence variant from any existing LightSwitch reporter vector

Cell-based screening service to measure the effects of compounds on a variety of biological pathways

Sequence Variant Assay Services to understand the functional impact of sequence variation on promoter or 3´UTR activity

Full screening service to validate the 3´UTR targets of specific miRNAs

Reduce labor costs by using our ready-to-use Lateral Flow Coupling Kit for magnetic and latex particles. No messy pre-preparation of reagents required. Simply pipette Anteo's water-based Activation Reagent onto your chosen particles to activate. Hands-on time for surface activation and coupling is 60 minutes. Magnetic particles are easier to use than gold. Magnetic separation removes the need to perform centrifugation and f…

Anteo’s ready-to-use Antibody Coupling Kit for magnetic, polystyrene and silica particles is a less hazardous alternative to covalent NHS/EDC chemistry. No messy pre-preparation of reagents required. Simply pipette Anteo's water-based Activation Reagent onto your chosen particles to activate. Hands-on time for surface activation and coupling is 60 minutes.                   With this kit, antibodies assemble in the correct…

Reduce labor costs by using our ready-to-use Magnetic Separation Coupling Kit. No messy pre-preparation of reagents required. Simply pipette Anteo's water-based Activation Reagent onto your chosen particle to activate. Hands-on time for surface activation and coupling is 60 minutes. This kit greatly reduces the risk of antibody damage, leading to less antibodies required for the experiment, increased antibody functionality,…

Range of kits from Alpha Laboratories.   The range includes: ELISAs Kits - The range of assay kits and ELISAs for popular chemistry parameters and disease markers can be performed easily in the laboratory LabAssay Kits - The microvolume LabAssay range of colorimetric-enzymatic assays is designed to be performed manually in a microtiter plate format to minimize sample volume requirement with most assays requi…

Tissue culture is one of the most widespread laboratory techniques. Primary cultures may be derived from blood or tissue explants and thousands of immortalised cell lines are now available from tissue culture collections. Alpha offer products to aid the preparation of optimal culture surfaces as well as pre-coated culture ware along with supplements for growth and differentiation.   The range includes: Cell Gr…

  Wako Laboratory Chemicals produces a range of chemicals and reagents that are recommended by Shimadzu for use with their automated protein sequencers. Alpha Laboratories is pleased to be able to supply these materials to customers in the UK who need them to support the operation of their sequencers.  

Alpha Laboratories offers a range of products to aid proteomic investigations from separation to sequencing along with the Phos-tag™ series specifically designed for analysis of protein phosphorylation. Products include: Automated protein sequencing chemicals and reagents Enzymes and inhibitors Mass spectrometry protein analysis Phos-tag™ Protein electrophoresis reagents Glycobiology Exosome Isolation Kit…