Separations Products & Reviews

The 1260 Infinity II Preparative LC System is an easy-to-use workhorse for automated sample injection when gradient elution is required for sample purification. The binary gradient pump deliver flow rates up to 50 mL/min for purification up to 30.0 mm id columns. This system is tailor-made for routine, high-throughput, laboratory-scale purification when milligrams to grams of starting material are available.

The 1260 Infinity II Preparative LC/MSD System can be configured with UV and MS detectors as well as multiple fraction collectors to meet your purification needs. Automated sample injection increases daily sample throughput and mass-based fraction collection maximizes purity and minimizes re-analysis.

The 1290 Infinity II Preparative LC System is designed for the purification laboratory that needs increased daily throughput by offering automated sample injection and fraction collection, smooth control of LC valves, and flexible access to up to four analytical columns and six preparative columns.

The 1290 Infinity II Preparative LC/MSD System enables high-throughput purification, delivering high-quality compounds, for example, for biological screening, an important part of drug discovery.

The 1290 Infinity II Autoscale Preparative LC System is a scalable, workflow-based solution that facilitates automated scale-up from analytical method scouting to optimized purification.

The 1290 Infinity II Autoscale Preparative LC/MSD System is the ultimate workflow solution for direct scale-up from analytical scouting to gram-level purification of target compounds.

The 1260 Infinity Multidetector Bio-SEC System is completely metal-free and comprises light scattering and dynamic light scattering to allow determination of protein shape and size without the need for SEC column calibration.  For research use only. 

The 1290 Infinity III HDR-DAD Impurity Analyzer System has a 30 times higher dynamic range, 30 times higher UV sensitivity, plus UHPLC resolution and speed. Detect and quantify every component in your sample in a single run with superior area precision for low-level impurities.

The 1290 Infinity III High-Throughput System achieves highest analysis speeds utilizing the autosampler capacity of up to 16 cooled microplates and shortest cycle times without compromising on the robustness you need for an ultrahigh-performance liquid chromatography (UHPLC) system.

The 1290 Infinity III Method Transfer System features the Intelligent System Emulation Technology (ISET), which is specifically designed for both HPLC and UHPLC method transfer.

The 1260 Infinity III Method Development System provides robust and reliable technology for everyday automated HPLC method development challenges. An increased performance and flexibility are provided by the 1260 Infinity III Prime LC instrumentation.

The 1290 Infinity III Method Development System is a high-performance UHPLC method development instrument that provides maximum flexibility and performance to solve even the most complex method development challenges.

The 1260 Infinity III Multi-Method System offers maximum system utilization with minimum manual interaction. Give multiple users HPLC access to their personalized methods - all on one system. This HPLC multi-method system hosts the different everyday HPLC methods of multiple scientists and provides automated switching to run the personalized methods without the need of manually changing column or solvent.

The 1290 Infinity III Multi-Method System offers highest system utilization and automation with multiple method UHPLC capabilities for different users at the same system. This UHPLC Multi Method system hosts different methods on one system, backed by highest chromatographic performance, to give multiple scientists access to their personalized UHPLC methods.

The 1260 Infinity II SFC/UHPLC Hybrid System allows you to perform supercritical fluid chromatography (SFC) and ultrahigh-performance liquid chromatography (UHPLC) on a single instrument. The system supports pressures up to 600 bar in SFC mode and up to 800 bar in UHPLC mode. Switching between the two modes is easy and can be fully automated.

The 1260 Infinity III Amino Acid Analysis System provides a complete solution for the automated HPLC amino acid analysis. It combines the latest developments in HPLC instrumentation and column technology with proven precolumn derivatization chemistry for fast and sensitive amino acid analysis.

The 1290 Infinity II GPC/SEC System is a complete GPC/SEC analysis solution that is capable of both analytical- or microscale operation. The low-volume refractive index detector enables microscale operation, which offers several key benefits, including shorter run times for higher sample throughput, ultralow dispersion for improved resolution, and lower solvent usage and waste disposal in order to reduce costs.

The 1290 Infinity III High Speed Pump uses high-pressure mixing for UHPLC gradient formation and solvent blending from up to two solvents at pressures up to 1300 bar and flow rates up to 5 mL/min.

The 1260 Infinity II Preparative Binary Pump is an affordable high-pressure gradient pump for LC purification. The pump offers a dynamic flow rate range from 1 to 50 mL/min at up to 420 bar, allowing workflows on columns from 9.4 to 30 mm inner diameter.

The 1260 Infinity III Flexible Pump is a quaternary UHPLC pump that provides gradient formation and solvent blending from up to four solvents. This UHPLC pump enables quaternary solvent delivery at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Isocratic Pump provides isocratic solvent management for HPLC, UHPLC, and GPC/SEC applications. This pump operates at pressures up to 600 bar and flow rates up to 10 mL/min.

The 1260 Infinity III SFC Binary Pump is a supercritical fluid chromatography (SFC) pump that supports high-pressure gradient formation and precise mobile phase delivery up to 5 mL/min and 600 bar. It can be used with a broad range of chiral and achiral columns, and ideal for fast, high-throughput SFC and SFC/MS applications.

The 1290 Infinity III Vialsampler combines sample management and column handling in a single autosampler module. The Vialsampler injects from up to 132 standard 2 mL vials and has a pressure rating of 1300 bar. 

The 1290 Infinity II Preparative Open-Bed Sampler/Collector is the solution for automated, high-capacity management of sample injection and fraction collection in semipreparative and preparative-scale LC purification workflows. The X-Z-theta axis probe uses novel robotic technology to minimize sample carryover during movements between fraction containers. Sample volumes can be injected from microtiter plates, vials, or vessels…

The 1260 Infinity III Multisampler is a multipurpose autosampler that handles vials and microplates. Injecting at pressures up to 600 or 800 bar, the Multisampler is a compact module with a capacity of up to 6,144 samples, all within the footprint of an Agilent LC stack.