Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Humanized Mouse Models

Creative Biolabs

We specialize in Humanized Mouse Models, overcoming species limits for in vivo human-specific disease studies. We construct diverse systems, including Immune Checkpoint knock-in and PBL/SRC SCID mice, by engrafting functional human cells to power crucial research in oncology, infectious diseases, and immunity.

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NucleoCounter® SP-100™ sperm cell counter

ChemoMetec

The NucleoCounter® SP-100™ sperm cell counter offers unique ease of use and effective determination of total sperm concentration and viability in semen samples from ejaculates or extended doses. The NucleoCounter® SP-100™ is very simple to operate and the measurements can be performed by operators with only limited training in laboratory work.

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GMP Proteins

Creative BioMart

Manufactured under strict Good Manufacturing Practice guidelines, these proteins are designed for use in preclinical, clinical, and therapeutic applications where quality and regulatory compliance are paramount.

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PROTAC Targets

Creative BioMart

Recombinant proteins specifically relevant as E3 ligases or target proteins for Proteolysis Targeting Chimeras (PROTACs), enabling the development of this novel targeted protein degradation technology.

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Flareâ„¢

Cresset

Flareâ„¢ is a ligand-based and structure-based drug design platform. Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.

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Sparkâ„¢

Cresset

Sparkâ„¢ is a powerful scaffold hopping and bioisosteric replacement solution that generates highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps.

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Discovery CRO

Cresset

Cresset Discovery is a premier computational chemistry CRO with a proven track record delivering high impact drug discovery projects. From ideation to synthesis and biological results, their expert CADD scientists are the best at what they do. Working alongside you from the ground up, they apply the best in silico techniques, and give expert advice and guidance, to accelerate your assets through the pipeline.

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Yeast Controlâ„¢ - Cell Cycle

Sysmex Europe SE

Yeast Controlâ„¢ - Cell Cycle. Reagent kit for staining of yeast nuclear DNA after cell fixation by ethanol. This allows determination of total DNA and cell cycle analysis, which varies during the fermentation process. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Cube and CyFlow Space flow cytometers.

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Yeast Controlâ„¢ - Glycogen

Sysmex Europe SE

Yeast Controlâ„¢ - Glycogen. Reagent kit for measuring glycogen in yeast cells, following a cell fixation step. Glycogen content varies during the fermentation process: it is accumulated in yeast during the early exponential phase and utilized during nutrient depletion. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Cube and CyFlow Space flow cytometers.

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Yeast Controlâ„¢ - Neutral lipids

Sysmex Europe SE

Yeast Controlâ„¢ - Neutral lipids. Reagent kit for measuring neutral lipids in yeast. Neutral lipids serve as a storage substance and confer stress tolerance to yeast by stabilizing the membrane and protect cells against bacterial invasion. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Cube and CyFlow Space flow cytometers.

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Yeast Controlâ„¢ - Trehalose

Sysmex Europe SE

Yeast Control™ - Trehalose. Reagent kit for measuring trehalose in yeast after a cell fixation step. Trehalose assists in stabilizing the yeast cell membrane during nutrient depletion and starvation, and other stresses as heat shock or ethanol exposure. It thus serves as a major stress tolerance indicator. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Cube and CyFlow Space flow cyto…

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Yeast Controlâ„¢ - Viability

Sysmex Europe SE

Yeast Controlâ„¢ - Viability. Reagent kit for yeast cell counting and viability testing (differentiation between living and dead cells), both of which are relevant parameters in growing yeast cultures. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Cube and CyFlow Space flow cytometers.

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