Drug discovery > Pre-Clinical Development Products & Reviews

The Lactate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of L-lactate in biological samples. Lactate is produced by glycolysis, a major metabolic pathway responsible for glucose homeostasis and energy production (1,2). Once considered merely a byproduct of glycolysis, lactate is now considered an important regulatory molecule of intermediate metabolism involved in cancer development, diabet…

The Glucose-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glucose in biological samples.

A Fluorometric Method for Estimating the Number of Nonviable Cells Present in Multiwell Plates

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

A Simple, Non-Radioactive Assay to Measure Glucose Uptake Inside Cells

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ MT Cell Viabiilty Assay measures viability of cells in a non-lytic, real-time live-cell format, saving time, cells and reagent costs.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.

The CellTiter-Blue® Cell Viability Assay provides a homogeneous, fluorescent method for monitoring cell viability. The assay is based on the ability of living cells to convert a redox dye (resazurin) into a fluorescent end product (resorufin). Nonviable cells rapidly lose metabolic capacity and thus do not generate a fluorescent signal. The homogeneous assay procedure involves adding the single reagent directly to cells cultur…

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

The Promega CytoTox 96® Non-Radioactive Cytotoxicity Assay is a colorimetric alternative to radioactive cytotoxicity assays. The CytoTox 96® Assay quantitatively measures lactate dehydrogenase (LDH), a stable cytosolic enzyme that is released upon cell lysis, in much the same way as [51Cr] is released in radioactive assays. Released LDH in culture supernatants is measured with a 30-minute coupled enzymatic assay that result…

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

ETHOS™ X microwave extraction line allows quick heating of the cannabis material for terpene isolation. Solvent-free extraction process takes only a few minutes and prevents any thermal degradation often noticed during use of conventional extraction methods. The fresh and characteristic taste of strain-specific cannabis is maintained, and high-quality terpenes are assured. The ETHOS X 2.0 is our latest generation of benchtop…

Proteinase K from Tritirachium album ELEVATE  

Proteinase K from Tritirachium album ELEVATE

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.

Stainless Steel Manifold -available in single, 3 and 6 station designs. The 3 and 6 multi-station manifolds allow the simultaneous processing of multiple samples.

A fully-integrated turnkey Anesthesia System immobilizes small animals when taking pictures with the iBox Explorer2 Imaging Microscope, iBox® Scientia™, and iBox® Spectra™ Imaging System.   

Compact and amazingly versatile, benchtop MixMate can be used for virtually any mixing application. It accommodates micro test tubes, PCR plates, deepwell plates and MTPs. It features an integrated vortex ing function and an operating concept that is as simple as it is intelligent. 2DMix-Control: uniquely fast and controlled mixing movement Current findings show that rpm speed is not the only determining factor in effici…

The Eppendorf epMotion 96 is a semi-automated electronic pipette for fast & precise parallel 96 channel microplate processing.   It is an easy to use bench top system for high precision pipetting in 96 & 384 well plates. Without changes to the system, a large volume range of 0.5 µL to 300 µL is available for convenient use over a range of applications. Its ergonomic design and intuitive handling makes the epMotion 96 a g…