Life sciences encompass a diverse range of scientific disciplines focused on the study of living organisms and their interactions with the environment. From basic life sciences (such as cell biology, genetics, immunology, and microbiology) to applied life sciences (such as disease research, multi-omics, and biotechnology), this broad field explores the fundamental processes of life and drives advancements in disease research, patient care, and our overall understanding of living organisms. Discover the endless possibilities of life sciences and their impact on shaping a healthier and more sustainable world.
Lysate Direct PhyTip® Column Technology consists of novel purification columns that are composed of a pipet tip containing plasmid DNA binding resin and a thin, inert frit screen at the end of the tip to retain the resin. The unique design of the column allows for DNA binding directly from cell lysates in the presence of precipitates and debris without sample clearing. By eliminating the need for centrifugation or filtration,…
The Pippin Prep is a preparative electrophoresis platform for collection of size-selected DNA samples. The system automates DNA size selection using disposable, pre-cast agarose cassettes to extract fractions according to user-defined software input. Samples are electro-eluted from agarose and collected in buffer. The platform is used for the construction of next-gen sequencing libraries. The system collects fragments (depend…
The Pippin Link Group Control is the best way to reproducibly provide the highest quality size-selected DNA in high-throughput. It provides hardware and software for running up to eight Pippin Instruments from a laptop PC. Three linked-Pippins can produce up to 96 size selections in one day.
WHEATON BioBanking Solutions is a comprehensive offering of high quality products and customized services for your cryogenic needs.Whether you require the storage of irreplaceable samples in glass cryogenic ampules or plastic cryogenic vials, bar coding options for sample traceablity or for color coded storage and freezer boxes, WHEATON provides you with the tools that make your job easier and more efficient while having the c…
Surveillance Imaging for 24/7 Lighting ConditionsNOCTURN Camera provides a simple, compact solution to 24/7 imaging requirements across a wide variety of lighting conditions including low-light imaging. NOCTURN’s compact size and low power consumption makes it ideal for man-portable vision systems as well as unmanned remote surveillance. On-board electronics provide automatic processing for gain control and image correction, w…
Modular microscope-based high content screening solution
Total internal reflection fluorescence microscopy (TIRFM) has firmly established itself over the last few years as a key technique in the investigation of molecular interactions at or near the cell surface.Olympus is experienced in providing advanced TIRFM solutions and cell^tirf takes this technology to the next level with a series of peerless features such as highly advanced optics, unique independent laser control and excep…
The UIS2 mirror units are optimized for maximal fluorophore performance, producing uniform and highly efficient light transmittance. The filter efficiency allows for the use of weaker excitation light, thereby minimizing photobleaching and damage to the sample.
The new PHOTONIS Ion Mobility Spectrometer (IMS) Analyzer is a complete integrated assembly for simplified IMS analysis that features high resolving power (64-150) in a compact design. The unit combines PHOTONIS’ patented Resistive Glass products with a new robust ion gate technology to create an IMS analyzer which improves resolution and simplifies serviceability. Key components of the IMS Analyzer are made from Resistive Gla…
forensicGEM™ has been formulated for high-throughput DNA extraction from crime samples. The forensicGEM™ kits have been specifically designed to be compatible with high-multiplex STR profiling kits and all reagents are rigorously Quality Controlled to test for efficacy and for the absence of human DNA. ZyGEM technology is ideally suited to the large-scale batch processing of reference samples for forensic analysis. Validated b…
RFP -Trap® - use your fluorescence fusion as tag for biochemical studies Curiously RFP, a widely used labeling tag in cell biology, is rarely used for biochemical analyses. This may be due in part to limited RFP antibody availability and specificity as well as co-eluted heavy and light antibody chains that interfere with subsequent analyses. Superior results in a fraction of the time The ChromoTek RFP-Trap® overcomes these pro…
GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…
Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…
Fusion of proteins to Glutathione S-Transferase (GST) of Schistosoma japonicum is a common technique to increase solubility and expression level of a protein. Furthermore, GST-tagged fusion proteins are often used in protein-protein interaction studies. Both approaches require highly specific tools to isolate and detect GST fusion proteins. GST-Trap The GST-Trap is a highly specific and robust GST-binding protein coupled to ma…
DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…
Proliferating cell nuclear antigen (PCNA) is a homotrimeric ring-shaped protein that encircles DNA and acts as a loading platform for multiple, transiently interacting factors participating in various DNA transactions. PCNA plays a key role in DNA replication, repair, cell cycle regulation, and post-replicative transactions like DNA methylation and chromatin remodeling. All these cellular processes are regulated by a complex n…
Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…
RNA polymerase II features a large carboxyl-terminal repeat domain (CTD) that consists of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Differential phosphorylation in this CTD orchestrates accessibility for various co-factors of the transcription complex. Using the phosphorylation specific antibodies it is now possible to determine specific phosphorylation states. In addition to phosphorylation specific antib…
The VisiTIRF Fluorescence Imaging System from Visitron Systems is the ideal solution for the analysis of finest structures or surfaces. The flexibility of the VisiTIRF system and the use of scientific digital CCD camera systems with optimal resolution, speed and sensitivity allows for the adaptation of customized application and configuration. For fluorescence illumination Visitron use solid state lasers or laser diodes . The…
The DH-40iL Microincubator is designed for imaging live cells under constant temperature and atmospheric conditions. This versatile incubation system enables high resolution image analysis, fluorescence microscopy, and time-lapse imaging studies while accommodating both upright and inverted microscopes. Designed to provide complete environment control for either the Series 40 open bath chambers or 35 mm cell culture dishes. E…
The Bold Line Top Stage Incubator H301 is the latest release from OKOLAB in terms of Top Stage incubation. It delivers superior temperature stability, humidity, CO2 and Oxygen control in a fully integrated fashion. The Bold Line Top Stage Incubator H301 Equipment: Incubating Chamber: fits in the microscope stage and holds the specimen. It is equipped with heated glass lid and Temperature and Humidity sensors. T Unit: Bo…
The Water Jacket Incubator provides superior incubation stability above and below room temperature. Water is pumped from a water bath into the base plate and into the lid, which are both Water Jackets. Temperature Control Mechanism Temperature is directly measured inside a reference Petri-dish and is controlled by circulating water from a water bath into the Water Jacket Chamber. The Temeprature Controller reads the temperatur…
