Drug discovery > Lead Discovery Products & Reviews

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Inflammation and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray pla…

Real-Time qPCR assays for Signal Transduction and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Real-Time qPCR Case, Immersion Fluid, Frame Adhesive and Plate-File CD.

An acetyl-biotinylated substrate recognized by a Eu3+ anti-acetyl MAb and SA-XL665, which is used in activator screening or to test an High Throughput SIRT1 inhibitor.  The level of enzymatic activity is inversely proportional to the amount of signal produced in the system. For more information please visit Cisbio Bioassays website.

VICI introduces the GC detector where the PDD (pulsed discharge detector) utilizes a stable, low-powered, pulsed DC discharge in helium as the ionization source. The D-2 is a dual mode, universal detector system which can be retrofitted to your older GC. The D-2-I is a helium photoionization detector, optimized for trace level work with packed columns. The stand-alone systems include detector, controller, electrometer, helium…

Pulsed discharge detector Model D-3 is designed for plug-and-play installation on Agilent GC's, with models available for the 6890 and 7890. The D-3 is optimized for trace level work in the helium photoionization mode, and utilizes the electronics and power supply of the host GC. Model D-5 is optimized for electron capture detection. Available for 110 VAC and 230 VAC.

Model D-5 is a pulse discharge GC detector designed for plug-and-play installation on the Agilent 6890. The D-5 is optimized for trace level work in the electron capture mode, and utilizes the electronics and power supply of the host 6890. Model D-3 is optimized for helium photoionization detection. Available for 110 VAC and 230 VAC.

Model D-4 a GC Detector available in versions for easy installation on most of the GC's in current use, including the Varian 3800, Shimadzu 14 and 17, ThermoFinnigan Trace, Mega, and Top, and Hewlett Packard 5890. The D-4 is single mode, optimized for trace level work in the helium photoionization mode. Available for 110 VAC and 230 VAC.

Model D-6 is a single mode GC detector, optimized for trace level work in the electron capture mode. IT is available in versions for easy installation on most of the GC's in current use, including the Varian 3800, Shimadzu 17, ThermoFinnigan Trace, Mega, and Top, and Hewlett Packard 5890.  Available for 110 VAC and 230 VAC.

Reduced breakdown liners Our improved injection port liner reduces breakdown of endrin and DDT during injections while increasing the interval between liner changes. The problem DDT and Endrin are easily degraded in the injection port; with non-deactivated liners and those filled with non-deactivated glass wool, Endrin breakdown can be as high as 98%. EPA method 8081A states "If degradation of either DDT or Endrin exceeds 15%,…

Permeation tubes are small, inert capsules containing a pure chemical compound in a two phase equilibrium between its gas phase and its liquid or solid phase.  They are used to generate a stable concentration of a specific trace chemical. At a constant temperature, the device emits the compound through its permeable portion at a constant rate. They are typically inserted into a carrier flow to generate test atmospheres for c…

Patented G-Cal permeation tubes offer a proven and repeatable means of generating a desired gas or vapor concentrations. The permeant gas escapes through the proprietary membrane system and mixes with a carrier gas (nitrogen is the most common) at a controlled flow rate to obtain a known mixture in ppm or ppb. Applications include calibration of gas monitoring systems and chromatographs, accuracy check of gas detectors, and ge…

Ultra-high capacity for the contaminant of interest; either Moisture, Hydrocarbons, Oxygen, Sulfur and Mercury. For applications with a single contaminant of interest, high capacity contaminant specific traps are your best option, since they generally have four times as much capacity for the specific contaminant as a purifier. This translates to a capacity that exceeds twelve standard type "A" tanks of gas or the equivalent of…

VICI AG heated helium purifier provides point-of-use purification of helium or other noble gases, such as Ar, Ne, Kr, and Xe, to sub-ppm levels of reactive gaseous impurities, removing even nitrogen and methane. The nitrogen purifier is similar, purifying nitrogen to sub-ppm levels of gaseous impurities. The miniature version of each purifier is designed to be installed in a GC’s flow path immediately upstream of the injector.…

Gas purifiers for specific gases designed to go in-line with the carrier or detector gas supply, these gas purifier modules dramatically reduce contaminant PPM levels in helium, hydrogen, nitrogen, or air. They decrease baseline noise and increase GC/MS sensitivity and replace three traps with one gas purifier.This line includes original equipment gas purifiers for the Agilent Mass Spec and LC Mass Spec. Additional specialized…

Syringes used to fill a loop on a sample injection valve have blunt, smooth ends. The end of the needle must contact the bottom of the valve’s fitting detail uniformly and seal on the outside of the tip to deliver sample with any repeatability. All VICI Precision Sampling syringes for valve injections have smooth, burr-free ends that fit the valve fitting details perfectly. The standard HPLC syringe is our basic C-160 with a 2…

Syringes used to fill a loop on a sample injection valve have blunt, smooth ends. The end of the needle must contact the bottom of the valve’s fitting detail uniformly and seal on the outside of the tip to deliver sample with any repeatability. All VICI Precision Sampling syringes for valve injections have smooth, burr-free ends that fit the valve fitting details perfectly. The standard HPLC syringe is our basic C-160 with a 2…

Hollow, flow-through plunger with integrated 3-way valve designed for liquid and gases, with a push button on/off valve at the front end. The new Precision Sampling hollow plunger syringe with two integrated valves opens a whole new world of application possibilities: Dispense a viscous sample more easily by introducing it into the rear of the syringe instead of drawing it up through the needle. Eliminate sample-to-sample cros…

The Dual Layer PEEK tubing eliminates any concern that a critical sample stream could be contaminated by pigments used to color code the tubing.  The pigmented layer surrounds a separate but integrally-bonded inner layer of natural PEEK. The 1/16" OD tubing is available in standard sizes, or in OEM quantities with any ID you specify, from .002" to .030". The ID tolerance of ±.001" is equivalent to or better than that of tubing…

CAS SciFinder -  The First Choice With SciFinder from CAS, you can increase your productivity and achieve faster breakthroughs Advancing the pace of research, Chemical Abstracts SciFinder search allows you to get results fast without compromising precision and accuracy. CAS SciFinder allows you to explore a wealth of information using sophisticated search and analysis technology. Chemical Abstracts SciFinder is a research d…

STN is an online database service that provides global access to published research, journal literature, patents, structures, sequences, properties, and other data. 

Acquire, Analyze, Manage, and Share Mass Spectrometry Information MassLynx™ Software increases the speed at which you can convert your sample data into valuable knowledge. It provides you with the fundamental platform to acquire, analyze, manage, and share your mass spectrometry information. MassLynx intelligently controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer a…

Economical, high efficiency columns to purify and/or characterize proteins, peptides, and other biomolecules including antibodies, aggregates, and PEGylated proteinsHigh performance: Analytical and preparative BioSep columns offer high resolution, maximum efficiency, and exceptional peak asymmetryImproved recovery: Extremely inert media offers advantages for accurte quantitationFlexible method development: 3 phases options (20…

In order to provide you with the most advanced tools for GPCR cell-based assays HTRF Technology now incorporates Lumi4®-Tb chemistry. Lumi4®-Tb is the first and only TR-FRET terbium cryptate, and is fully compatible with all existing HTRF readers. Therefore IP-One Tb offers new levels of sensitivity and performance in cell-based assays.

The AutoSpec Premier™ incorporates Waters’ unique EBE, double-focusing geometry with the extra-wide gap magnet of the proven Ultima NT System. This latest development in magnetic sector technology provides an unmatched combination of high sensitivity, high resolution, and low background noise.The AutoSpec Premier is a powerful platform for high-resolution selected ion recording applications, such as dioxin, polychlorinated bip…

Developed for your most demanding LC/MS/MS quantitative applications, the Quattro Premier™ XE tandem quadrupole mass spectrometer features the highest levels of sensitivity, selectivity, robustness, speed and accuracy. To maximize the analytical advantages of your ACQUITY UPLC® System, the Quattro Premier XE operates at the highest data acquisition rates. Together, the ACQUITY UPLC® System and the Quattro Premier XE give you i…