Drug discovery > Lead Discovery Products & Reviews

Over 50 years of reproducible performance

Semi-preparative Columns with excellent batch-to-batch reproducibility

The popular Bondapak® C18 chemistry and Porasil® silica packing material are available in three different particle sizes, 10, 15-20, 37-55 micron, providing easy transfer of chromatography methodology from one particle size to another. You can utilize your existing 10 micron Bondapak or Porasil chromatography as a starting point for scale-up or, if you are developing a new purification protocol, investigate which preparative…

These columns provide accurate and precise molecular weight calculations in under 7 minutes! - Fast, accurate and precise molecular weight determinations - Increase sample throughput - Greatly decrease solvent consumption and disposal

Designed specifically for polymer characterization, the Styragel® columns are grouped into the HR series for low-to-mid molecular weight samples, the HT series for high-temperature applications, and the HMW series for high molecular weight samples. Specifically controlled styrene divinylbenzene formulations provide reproducible performance in your GPC applications.

The Envirogel high-efficiency GPC cleanup columns are specifically designed to remove low volatility, high molecular weight interferences, such as lipids and natural resins, from environmental samples as specified in EPA Method 3640A. In the past, the cleanup procedure for environmental samples was performed on low-efficiency GPC columns based on packing particle diameters of 37-75 micron (200 to 400 mesh) Bio-Beads S-X resins…

Sep-Pak Plates enable high throughput solid-phase extraction with the same silica sorbents that have been proven for years in Sep-Pak Cartridges. The plate design has been optimized for automated sample handling systems as well as for standard vacuum manifolds. Sep-Pak Plates are available with different silica sorbent mass selections to optimize sample loading.

For applications where the sample is neither volume or concentration limited, Waters offers 1 and 2mm Internal Diameter columns of various lengths for use on traditional HPLC MS inlets.As with Waters array of NanoEase™ columns, the same Waters reversed-phase packings are also available in these two column internal diameter offerings. Chemistry choices include: XBridge® Columns, CORTECS® Columns, XSelect Columns, Atlantis® Pola…

MassPREP™ On-Line Desalting Cartridges are an effective tool for the successful desalting of acidic, basic, and large globular proteins. The overall MassPREP™ desalting strategy provides an easy, fast (< 3 minutes), and reproducible approach for the effective desalting of proteins stored in physiological salt buffers prior to high resolution ESI-MS structural analysis.

The polar organic and the polar ionic modes have become increasingly popular largely because of their ideal compatibility with MS detection and preparative LC. Two years of extensive research at Astec in understanding these mechanisms has resulted in new possibilities for extending their effectiveness even further. Important changes in linkage chemistries and the silica and the silica have now led to the new CHIROBIOTIC V2 and…

Peptide maps generated by RP-HPLC provide valuable information about protein structure, stability, and purity. To be effective, the RP-HPLC column must be able to resolve a high percentage of the peptides in the sample. The more peptides, the better the information. Discovery BIO Wide Pore C18 gives unsurpassed RP-HPLC resolution of peptide maps from enzymatic digests. The improvements in silica and bonded-phase chemistry we h…

bed wt. 25 mg, volume 10 mL , (LRC), pk of 50 Application A class selective MIP phase for the multi-residue extraction of beta-agonists in urine, tissues, and other biological fluids. SupelMIP - Beta-agonists was developed for the selective extaction of a broad range o beta-agonists such as brombuterol, clenbuterol, formoterol, isoxuprine, mapenterol, ractopamine, ritrodine, salbutamol, salmeterol, terbutaline, tulobuterol, zi…

In 2008 Gentronix launches a new S9 protocol to extend the application of the GreenScreen HC assay to include the detection of genotoxic metabolites. Many pharmaceuticals only present a genotoxicity hazard after metabolism and such chemicals are called pro-mutagens or pro-genotoxins. Generally, although not exclusively, the liver is considered responsible for the “metabolic activation” (MA) of promutagens. However, none of t…

The SPECTRUM range of High Performance CCC (HPCCC) equipment is based on traditional liquid/liquid partitioning and extends the purification options available to chemists, in Discovery and Development, who are looking purify samples from mgs to 5-10 grams of material. The equipment is easily connected and interfaced into existing LC equipment and provides options when existing solid phase technology cannot obtain the resolutio…

The DE Midi range of High Performance CCC (HPCCC) equipment is based on traditional liquid/liquid partitioning and extends the purification options available to chemists, primarily in Development, who are looking purify samples from 5 grams to 1,000 grams of material. The equipment is easily connected and interfaced into existing LC equipment and provides options when existing solid phase technology cannot obtain the resolutio…

Complete range of high quality cuvettes for use in optical spectroscopy Kromatek now has a range of excellent low cost cuvettes manufactured from high purity silica and manufactured to ISO 9000. Optical transparency is guaranteed as is matching if buying sets of cuvettes.The Kromatek cuvettes are extremely competitively priced! And we have optical glass cuvettes for colorimetry and general teaching applications UV-Visib…

The Model 307 Oxidizer utilizes the patented "open/close" flame oxidation technology. The result: an oxidizer that will expand your experimental designs in liquid scintillation counting.

Scaling up is easier when using an HPLC media that provides near identical performance across all particle sizes and with increases in column diameter. The separation characteristics of each Phenomenex media offer unique selectivity for each type of application and significant production gains for maximum loadability and process economy. Achieve identical performance from analytical development to large process scale. Our Luna…

SecurityGuard offers a convenient and economical way to extend HPLC column lifetimes. Did you know a common cause of high backpressure, split peaks, broad peaks, baseline noise, baseline drift and loss of resolution is contaminants? The fact is all mobile phases contain some chemical contaminants or microparticulates, from the sample, solvent, or wear on the polymeric seals of the pump or injector. These contaminants can…

The Oasis® uElution plate format combined with the Oasis chemistries allow elution volumes as low as 25uL, eliminating the time consuming evaporation step, producing very clean extracts with a 5 to 10 fold increase in concentration.The Oasis® family of sample extraction products is designed to simplify and improve your sample preparation by combining the right sorbent chemistry, device format and methodology. Achieve robust, s…

Accessories and Consumables for FTIR and Dispersive IR instruments to fit virtually any manufacturer's instrument. But before you choose just any accessory check out the MIRacle and GladiATR. Not only the highest throughput single bounce diamond ATRs, but with robust Hastelloy top plates make for maximum durability and acid resistance. With an optional digital 'true force' gauge. These are truly remarkable accessories. Wi…

SCAT solvent safety systems have been designed to bring solvent safety to the laboratory. The specially designed caps for both solvent reservoirs and waste containers fit virtually any sized container. Certified by TUV in Germany these safety systems af guaranteed to protect your health in the laboratory. Recent legislation has meant the use of solvent safety systems are mandatory in a number of EU countries and several EU m…

FineView precision microplates for observing and measuring cell growth A range of precision microplates and cell culture plates with different materials for growing and observing cells. A new polymer film not only helps in the groth of cell cultures, but also allows better optical transmission for observing and measurement using spectrometers and plate readers A variety of culture plates including: Polymer film Glass…

With a fresh and customer focussed approach to Polymer Analysis, PSS is Germany's leading authority in Gel Permeation Chromatography, GPC and SEC. The most comprehensive range of products for standards, columns instruments and software coupled with more than twenty years experience in delivering customer oriented results. A complete range of standards for organic and aqueous GPC Columns for organic separations Columns f…

ELSD detectors - 3 models to choose from Model 100 ELSD – Simple OperationModel 300S ELSD – Advanced ControlModel 400 ELSD – Sophisticated Sytem Management Highest dynamic range 4.5 orders of magnitude Equal response between analytes High sensitivity even for semi-volatiles Independantly control the temperature of the nebuliser and drift tube