Drug discovery > Lead Discovery Products & Reviews

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Total volume is 190 µL; recommended working volume of up to 25 to 125 µL Conforms to standard microplate footprint and dimensions Without l…

This microplate has half the growth area of a standard 96 well plate Flat bottoms with 190 µL total volume White walled plates enhance luminescent signals and have low background luminescence and fluorescence Opaque walls to prevent well-to-well crosstalk Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Bulk packed 20 per bag

Nanospray kit introduced at HPLC 2001, Beyond Genome SAN JOSE, Calif. and CAMBRIDGE, Mass., June 19 -- Thermo Finnigan, a Thermo Electron (NYSE:TMO) business, and New Objective, Inc., which both supply essential products to proteomics research markets, are teaming up in a strategic supply agreement to introduce the NanoFlow Solutions Kit, which will greatly simplify the use of low-flow nanospray ionization for proteomics. The…

Single & double end fittings in stainless steel & PEEK collared connectors

The Direct Connection UNIGUARD allows the guard cartridge outlet to be directly placed against the analytical column inlet frit. Product detail: We recommend all analytical columns are protected by a guard cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard cartridge. We offer 10x1, 10x2, 10x3, 10x4mm guard cartridges in all our stationary phases to ensur…

The Javelin guard design is a one-piece format that can be installed without wrenches and requires no holder, which allows quick and easy replacement. Product detail: We recommend all analytical columns are protected by a guard column or cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard, so we offer 1.0, 2.1, 3.0 and 4.0 diameter Javelin guard columns in…

MultiSEP™ solid phase extraction wells from Thermo Electron offer robust and reproducible sample preparation and pre-concentration on a routine basis.Wells are available in pre-assembled plate format or as individual wells to allow customisable plates to be assembled by the user.Sorbent packings include the ever-popular silica based bonded phases and also include novel and unique chemistries for specialised applications. Multi…

HyperGEL columns are packed with porous polymeric beads with a precise pore size distribution so that solutes are accurately separated according to molecular size.High efficiency HyperGEL columns provide a minimum of 50,000 plates/metre for 5µm particle size. The columns are available for aqueous (HyperGEL AP) or organic (HyperGEL OP) separations.HyperGEL OP columns are offered in 7 pore sizes and 2 particle sizes to test mole…

Get maximum loading and efficiency from your preparative columns. Achieve high loading with Thermo Electron phases and column sizes up to 50mm ID and 250mm length. Our column packing and silica expertise ensures our preparative columns achieve optimum efficiency and lifetimes.Our BETASIL™ and Hypersil™ 100 phases are ideal for preparative separations. We recommend the separation is proven using an analytical scale column packe…

HyperREZ™ columns are specially designed for analysis of organic acids, alcohols, saccharides and carbohydrates. They employ a polymeric support with ligand exchange groups. The ligand exchange resins contain highly sulfonated cation exchange resins that have Group I, Group II or transition metals associated with the chromatographic surface.HyperREZ™ columns are based upon a polymeric resin that shows stability from pH 1 to 14…

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Without lids, lids supplied separately Sterilized by gamma radiation and nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 25 per bag

o   The benchmark in based deactivated silica columnso   Sharp peaks and improved symmetry for basic compoundso   Value and performance from a globally referenced column Product detail: DASH columns are packed to the same high standards as our analytical columns, and offer superioir chromatographic resolution in a design that eliminates the need for endfittings and wrenches during column change over. This makes column inst…

BioBasic 8 Columnso   Improved reproducibility, efficiency and column lifetimeso   Range of stationary phases to optimize selectivityo   Powerful resolution, even on short column lengths Product detail:BioBasic 8 columns provide exceptional reliability for separations of proteins, peptides, and other biomolecules through a combination of high purity silica and reproducible, stable bonding.  The proprietary bonding procedure en…

BetaMax Acid Columns o   High surface area area and bonded phase coverage for maximum retention, even in high percentage organic conditionso   Chemistries for acidic compounds Product detail: For alternative selectivity to traditional alkyl phases, we recommend you try the polar embedded phase BetaMax columns. The stationary phase contains urea groups embedded within the C12 chain, which extra interactions with samples to…

BETASIL C18 Columnso   Broad range of particle sizes and phases for wide method development optionso   High surface area and phase coverage for reproducibility and sharp peak shapes Product Detail BETASIL columns are based on 100Å pore size, fully deactivated type B silica to ensure sharp peaks and excellent reproducibility for the analysis of a wide range of compounds. The 100Å pore size gives a higher concentration of statio…

Fluophase RP Columns o   A range of perfluorinated phases for alternative selectivityo   Extra retention and selectivity for halogenated compoundso   Select from 100Å and 300Å pore sizes Product detail:For alternative selectivity to traditional alkyl phases, we recommend you try the perfluorinated phases of Fluophase columns. The stationary phase of Fluophase RP contains a perfluorinated C6 chain, where every hydrogen atom on…

BetaBasic 4 Columnso   Excellent peak shapes for basic compoundso   Superb stability at both low and high pH Product detail:BetaBasic 4 columns are based on a 150Å pore size, fully deactivated type B pure silica to ensure sharp peaks and excellent reproducibility for the analysis of basic compounds.  Due to stable bonding chemistry and excellent surface coverage, BetaBasic 4 columns show excellent peak shape for basic compound…

o   Excellent retention and alternative selectivity for polar compoundso   Completely stable under 100% aqueous conditionso   Ideal for LC/MS applications Product detail: AQUASIL C18 columns provide more retention for difficult-to-retain polar compounds due to a unique hydrophillic end-capping.  The combination of a moderate coverage C18 group and an additional polar group gives new selectivity compared to a traditional C18.…

Hyperbond™ is a cost effective alternative to µBondapak (a trademark of Waters Corporation). It is based on an irregular silica with 10µm particle size.

HyPURITY ADVANCE Columns  - offer exceptional chromatographic performance and is ideal for high throughoput laboratories with complex and variable sample types. Product detail: HyPURITY ADVANCE contains a polar amide group embedded within a C8 chain, and is fully endcapped. The columns are based on our metal free HyPURITY silica and, compared to other phases, produces a competely new selectivity. A polar functiona…

Hypersil BDS C18 Columnso   Sharp peaks and improved symmetry for basic compoundso   Value and performance from a globally referenced columno   Long column lifetimes with excellent column-to-column and batch-to-batch reproduciblity Product detail:Hypersil BDS C18 receives a special base deactivation treatment during silica material manufacture to reduce silanophilic activity. Hypersil BDS C18 is endcapped and suitable for chro…

o  Based on ultra pure 190 Å pore size silica for analysis of small molecules to proteinso  Extensive quality control tests to ensure the ultimate in reproducibility and performanceo  Unbeatable peak shapes for all sample typeso  Select from five phases for a wide range of selectivity options Product detail: HyPURITY C18 columns are based on the latest in silica technology - HyPURITY silica, which has less than 10ppm total m…

o   100% porous graphitic carbon with very different selectivity to reversed-phase silica columnso   Exceptional retention of very polar compoundso   Separation of structurally similar compoundso   Stable from pH 1 to 14 at high temperatures in a wide range of solvents Product detail: Hypercarb is a unique material for HPLC manufactured by Thermo Hypersil-Keystone. Hypercarb consists of fully porous spherical carbon particle…

o  Separate hydrophobic and ionic compounds in a single runo  Select from two mixed mode phases, using either cation or anion exchange combined with C18o  Retention of compounds is optimized using mobile phase pH, ionic strength and percent organic Product detail: Hypersil Duet columns are an ideal choice for unknown compounds and metabolism studies, as they can separate hydrophobic and ionic compounds in a single analysis…