Drug discovery > Lead Discovery Products & Reviews

The Specac Mini-Film Maker is designed to produce high-quality thin films of polymer and plastic materials for infrared transmission analysis. This product enables quick and easy hot pressing of samples at any temperature between ambient to 250°C, to give constant and reproducible thickness films over the range 50 to 500 microns with a formed diameter of 15mm. The Mini-Film Maker Kit includes the Mini-Film Maker Press with…

Specac offers a Short Pathlength Gas Cell that is ideal for routine gas and vapour spectroscopic analysis at room temperature, low pressures, and static or flow conditions. The cell has a fixed 10 cm pathlength, and is available in Pyrex™ and stainless steel. This Short Pathlength Gas Cell is supplied with a choice of NaCl, KBr, CaF2, BaF2, or ZnSe infrared transmission windows, and is mounted in an optical spectrometer wit…

A silicon ATR consumable technology which helps you zero in on your analysis. Zero cleaning. Zero risk of cross-contamination. Zero hassle.

TSKgel Protein C4 is a reversed phase HPLC column for the separation of intact proteins.

TSKgel mAb SW SEC Columns – Setting new Benchmarks for Antibody Analysis.

TSKgel UP-SW Series offers highest resolution based on established SEC technology.

TOYOPEARL AF-rProtein L affinity resin for the capture of mAbs and mAb fragments 

TOYOPEARL Sulfate-650F offers a high binding capacity for IgG across a range of pH values and conductivities

The TSKgel UP-SW3000-LS UHPLC column analyses biotherapeutics by size exclusion chromatography and is designed for the combination with MALS and MS.

Octave BIO intensifies your downstream processing productivity

SkillPak 50 (2.5 cm ID x 10 cm L, CV 50 mL) and 200 (5 cm ID x 10 cm L, CV 200 mL) pre-packed columns offer a reproducible and efficient solution for developing purification methods for biomolecules. They are the best solution to scale up methods developed on SkillPak 1 and 5 mL pre-packed columns.

The TSKgel ODS-100 HPLC column features a newly developed RP material for the separation of small compounds which is specifically designed to simplify difficult separations.

The AptaFluor® SAH Methyltransferase Assay Kit enables ultra-sensitive, direct detection of SAH—the universal product of methyltransferase reactions—using a riboswitch-based TR-FRET format. With no coupling enzymes required, it delivers high signal-to-background, Z’ ≥ 0.7, and is fully HTS-compatible for drug discovery and inhibitor screening.

BellBrook Labs’ Lead Discovery Services deliver expert support for hit-to-lead efforts. From inhibitor screening and potency profiling to residence-time, mechanism-of-action, and selectivity studies, their team tailors efficient enzymatic assays to your program—accelerating lead advancement with precision and flexibility.

The Transcreener® cGAMP cGAS Assay Kit offers mix-and-read fluorescent detection of cGAMP—the product of cGAS activity—with no coupling enzymes required. Available in FP or TR‑FRET readouts (far-red tracers minimize interference), it’s HTS-ready (Z’ ≥ 0.7), automation-compatible, and validated on 96‑, 384‑, and 1536‑well formats for enzyme kinetics, SAR, and inhibitor screening.

The CD73 activity assay for HTS and hit-to-lead. Measure specific activity of CD73 in a simple mix-and-read format. The kit is designed for compound library screening and follow-up inhibitor discovery.

The Transcreener dAMP Exonuclease Assay directly measures dAMP produced by exonuclease enzymes as they cleave polynucleotides. 

Simplify your workflow and save valuable laboratory time with the fully automated MACS® Sampler, a perfect extension for the MACS® Matchmaker instrument, allowing you to fully integrate automatization solution for your interaction studies.

With the MACS® Matchmaker you can experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity in complex samples. Unlock new possibilities in your research today – because every target deserves its perfect match!

PurePlus™ Deep Well Plates 96-well plates are designed for automation, high throughput screening (HTS), or heavy lab use. Each well holds either 1.2 mL or 2.2 mL and has smooth inside surfaces to ensure that all of your samples can be pipetted.

Accelerate precision oncology with Crown Bioscience’s high-quality human biospecimens—comprehensive, clinically annotated samples including tumor tissue, plasma, and PBMCs, optimized for multi-omics research and biomarker discovery.

ARRALYZE 8 Chamber Slide combines standard slide format with advanced nanowell technology, featuring 8 chambers with 127 precisely etched nanowells (0.4 × 0.4 × 0.225mm) per chamber. The borosilicate glass bottom (0.175μm thick under wells) provides superior optical clarity for high-resolution imaging while maintaining an inert environment. Includes 3 fiducials per chamber for easy navigation and precise cell tracking.

The Rapid_pH™ Automated 96 pH meter automates the pH measurements of samples in a 96 well format. The Rapid_pH allows samples to be processed in a fraction of the time compared to manual methods avoiding errors in both measurement and data registration. Full automation for well plates and other arrayed containers provides unattended runs and walk-away time.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Handle reagents on automated systems simply and economically.