Drug discovery > Basic Research Products & Reviews

Patch clamp automation for the price of a manual rig

The most affordable high throughput automated patch clamp on the market

The magnefect-nano from nanoTherics is full-feature, fully flexibly, easy-to-handle, fast and efficient cell transfection device. The system uses a patented technology which applies proprietary, oscillating magnet arrays to greatly improve transfection speed and efficiency. This results in significantly faster and higher transfection efficiencies over the traditionally used lipid-based and static magnet assisted transfection a…

Innova Biosciences, based on the Babraham Research Campus, Cambridge UK, has launched a family of assay reagents called PiColorLock™, to facilitate the measurement of the activity of phosphatases, ATPases and other Pi-generating enzymes in microplates. Unlike the traditional "Malachite Green" method, which is prone to precipitation problems, PiColorLock reagent is specially formulated to give a stable end-point signal, meani…

The RTCA Analyzer is an electronic analyzer that can, under the control of RTCA Software, measure electronic impedance of sensor electrodes at various signal frequencies. The RTCA Analyzer is capable of computer-controlled signal generation, processing and analysis, automatic frequency scanning and rapid measurement. The average measurement rate is approximately 15 seconds for a 96-well plate, or approximately 150 milliseconds…

ToxCount™ provides a two wavelength cell viability assay based on determination of live and dead cells. The assay uses fluorescent dyes that measure permeability of the plasma membrane of dying cells and the ability of living cells to retain intracellular esterases, respectively. Live cells are distinguished by the presence of ubiquitous intracellular esterase activity, determined by the enzymatic conversion of the non fluores…

ambr is an advanced microscale bioreactor system comprises 24 or 48 disposable micro bioreactor vessels (10-15ml) controlled by an automated workstation. For rapid evaluation of multiple bioreactor cultures in parallel. ambr is a better tool for cell line selection and devlopment amd offers significant reduction in cost per experiment.

The X-Cite® 200DC offers the ultimate combination of optical performance, short term stability and a built-in fast shutter. With the convenience and superior illumination uniformity found in all X-Cite® systems, the X-Cite® 200DC's intuitively easy-to-use design also includes light guide auto-detection to ensure optimized light coupling - every time. Novice and experienced microscopists will enjoy the flexibility provided by t…

Optimized Raman Solution for Life Sciences from HORIBA Scientific The XpIoRA INV is an inverted Raman microscope designed specifically for use with biological samples requiring analysis from the bottom and/or open access to the sample from the top. Like all other XpIoRA series of Raman microscopes, the INV features a small footprint, complete automation (autofocus, autoexposure, autovalidation, autocalibration), and ease of us…

AstraGene has been developed for the routine laboratory analysis of nucleic acids and proteins. With its specially developed through-the-tip measurement technology, your precious samples will never leave the pipette tip – speeding up analysis and protecting your sample. This simple system makes your work-flow as easy as just taking up the 2µl sample with the pipette, placing the pipette and tip in the holder and selecting th…

AstraTint is an advanced fibre optic coupled spectrophotometer that is dedicated to colour measurement and comparison; its high resolution CCD array detector making measurements in less than 2 seconds. AstraTint shows the sample’s position in the CIE colour space in the lower half of the screen with the L*, a*, b* and x, y, z co-ordinates to the right. If a reference has been measured the values are stored and displayed abov…

Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) DNase- and RNase-free Total well volume 180 µL

Superior Bead Recovery and Low Levels of False Positives Ensure Assay Reproducibility. Smooth well wall provides efficient bead recovery, ensuring reproducible results lot after lot High performance membrane does not trap microspheres in the membrane matrix In serological assays, Supor® membrane effectively removes IgG complexes, thus reducing nonspecific reactivity of the microspheres and reducing false positives New well des…

Robust Chemical Resistance Provides Compatibility with Harsh Organics. Chemically resistant materials provide a stable platform to process samples in organic solvents Inert materials of construction ensure complete recovery of samples and low non-specific binding New well design results in faster, more uniform filtration rates across the plate and reduces hold-up volume Innovative outlet tip geometry provides direct flow of sa…

The AcroPrep™ Advance filter plates for lysate clearance effectively remove cellular debris quickly and allow for the use of additional wash steps to maximize sample recovery. Filtration can be accomplished by either vacuum manifold or centrifugation, ultimately maximizing your choice in protocols. The purification of biomolecules (DNA, RNA and proteins) from prokaryotic and eukaryotic cell lines can be problematic. The AcroP…

EIA/RIA plates are tested on lot-to-lot basis and the certification results for each lot are made available upon request by contacting local Corning Life Sciences office High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity of approximately 500ng of mouse IgG/cm2 Ideal for immunoassays Recommended working volume of up to 75 to 200 µL Confor…

PicoStar is a state-of-the-art ultrahigh repetition rate, fast gated intensified CCD camera. The camera is ideally suited for use in conjunction with high repetition rate mode-locked lasers. Typical applications are: time-resolved imaging and spectroscopy, fluorescence lifetime imaging microscopy, single molecule or quantum dot imaging and spectroscopy, multifocal multiphoton microscopy, fluorescence resonance energy transfer…

TauTec’s TriMScope, a state-of-the-art multifocal multiphoton microscope, is based on a patented beam divider that splits up an incoming laser beam into up to 64 beamlets which are scanned simultaneously in the object plane. This results in either 64 times brighter images or 64 times higher image rates compared to standard single beam multiphoton scanning microscopes. The foci in the object plane are aligned in a single line a…

TauTec is now offering customized, turn-key time-resolved imaging systems incroporating state-of-the-art intensified, picosecond gated ICCD camera, choice of excitation laser source (mode-locked lasers up to 100 MHz), optical microscope (inverted or upright), imaging spectrograph and the required accessory electronics. The modular system is suitable for various applications such as FLIM (Fluorescence Lifetime Imaging Microscop…

Imager QE is a 12 bit CCD camera for digital imaging. It is based on an interline chip with 70% QE. It can be read out at 16MHz pixel rate with an rear out noise of 4e.

Comet Assay IV's unique single-click scoring method and ultra-fast live video picture make it the most efficient and easy-to-use system available for measuring DNA damage using single cell gel electrophoresis. There are no complicated parameters to adjust and no hardware to install - simply connect the camera and start scoring. Working closely with leading experts in the field, Perceptive Instruments have released Comet Assa…

The AMES STUDY MANAGER is an integrated suite of software for conducting Ames tests according to regulatory guidelines. It has been designed to fulfil the requirements of safety assessment laboratories in pharmaceutical, medical device and chemical companies as well as Contract Research Organisations. The system is highly flexible, accomodating almost any experiment design and allowing sharing of controls between experimen…

Rapid, manual counting of colonies

ColorKits are designed to facilitate the measurement of the activity of phosphatases, ATPases and other Pi-generating enzynes in microplate assays. Each Kit contains a phosphorylated substrate for a particular class of enzyme, together with a carefully optimised PiColorLock detection reagent, Pi standard, 2x96-well plates and a selection of buffer concentrates for optimisation of assay conditions with the enzyme of interest.…

PiColorLock Drug Discovery Kits are designed to facilitate the measurement of the activity of potential inhibitors of phosphatases, ATPases and other Pi-generating enzymes in microplates. The Kits combine a purified recombinant human enzyme target, phosphorylated substrate, Pi standard and 2 multiwell plates. Each Kit is also supplied with a carefully optimised PiColorLock detection reagent and a selection of buffer concentr…