Drug discovery > Basic Research Products & Reviews

The QBC ParaLens Advance microscope attachment is a unique solution to fluorescence microscopy in that it combines the critical components of an epi-fluorescence microscope, namely the light source and filter set, with a microscope objective in a compact, durable format that can transform virtually any compound light microscope into an epi-fluorescence microscope. Utilising LED technology, the ParaLens light source lamp has a…

Lids are made of rigid polystyrene Lids have a corner notch on the A1 corner to correspond to the corner notches found on all Corning® microplates Lids do not fit Corning 2 µL 1536 well microplates or 2 mL 96 well storage blocks Sterilized by gamma radiation

Advanced features and careful design ensure the reliability of Microtiter microplates. In your immunoassays coating and washing are always even, and the recessed bottom keeps the surface clean and scratch free ensuring high optical performance. The microplates are available with different binding characteristics and formats.Product detail:Thermo Microtiter products have binding characteristics that include ImmulonTM hydrophobi…

White Microtiter microplates are designed for use with light emitting markers. Pigments have been carefully selected to optimize assay performance. The white pigment eliminates cross talk while optimum reflection enables best performance in luminometric applications with low signals. These microplates are available in different formats and binding characteristics. Product detail: Thermo offers a selection of Microtiter micro…

Thermo black and white microplates help you to optimize your assay performance in fluorescent applications. These microplates are designed for use with light emitting markers, having carefully selected pigments to eliminate cross talk and reduce background signals of your assays. Different binding characteristics and formats are available. Product detail:Microtiter Microfluor microplates and universal/enhanced binding plates…

Thermo 384 well Microtiter microplates offer you either round or rounded square well shapes and binding characteristics as well as pigmentation according to your choice. Available in clear, white and black versions, these microplates are suitable for a wide range of measurement techniques. The 384 well format enables higher sample density thus lowering the consumption of reagents. Product detail: Thermo wide range of 384 w…

These clear bottom microplates are sterile and thus ready to cultivate bacteria and fungi. TC treatment makes them perfect for mammalian tissue culture with no need for chemical treatments. They are individually packaged with lid and their unique design helps to eliminate cross-talk. The microplates are perfect for microscopic viewing and also suitable for top and bottom reading instruments. Low background fluorescence and lum…

Streptavidin coated wells of the BioBind microplate offer biotin mediated binding for small or hydrophilic molecules. This surface is ideal for e.g. peptides, oligonucleotides and DNA hybridization assays. The streptavidin-biotin bond is extremely strong and stable, and utilizing this system problems associated with steric hindrance during the binding procedure can be avoided. Product detail: BioBind - Streptavidin Coated…

Hamamatsu’s brilliantly designed ORCA-Flash4.0 is truly a game changer in the world of scientific imaging. Built on a revolutionary new Gen II sCMOS detector, the ORCA-Flash4.0 is the first sCMOS camera that challenges the performance of all CCD, EM-CCD, and Gen I sCMOS cameras. With its combination of low noise and high quantum efficiency, the ORCA-Flash4.0 delivers unprecedented sensitivity as well as high dynamic range, bla…

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SeqSolve™ is an advanced and user-friendly software solution for the tertiary analysis of Next Generation Sequencing (NGS) data. By integrating state-of-the-art bioinformatics methods into one-click analysis workflows, SeqSolve is the only software able to provide scientists with such a combination of both cutting edge and intuitive user experience. Its Click And Go® technology enables the automatic processing of the data, whi…

The Sciclone™ G3 NGSx workstation is a complete benchtop solution for the automated construction of up to or greater than 96 libraries per day. For Research Use Only. Not for use in diagnostic procedures.

5 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…

An arrayed or non-arrayed BAC library is the preferred choice for downstream applications such as hybridization screening; full-genome sequencing; BAC end sequencing or physical mapping projects. Amount of clones received is based on a guaranteed coverage and 120Kb average insert size. HMW DNA isolation and QC by HMW DNA enzymatic digestion are included. Deliverables for ARRAYED BAC library: Clones will be arrayed and amplifie…

A pooled BAC library is an invaluable tool for PCR-screening. It allows for the easy retrieval of BAC clones of interest. This type of library is especially useful when genome size is large and creating an arrayed library is cost-prohibitive. We typically construct a minimum 5X BAC library and BAC clones are then pooled and distributed in 96-well plates. Each well will contain about 400-500 original BAC clones. HMW DNA isolati…

Our cDNA libraries feature full-length-enriched and high quality size-fractionated cDNA. cDNA library construction is usually done in slightly-modified versions of pBluescript or pcDNA3.1. Insert sizes will range from about 0.5Kb to 4Kb. Concerning QC steps, we evaluate the average insert size, empty clone rate and clone concentration/tube before shipping out. We always provide a gel picture of randomly selected clones showing…

APAgene™ GOLD Genome Walking Kits are designed to rapidly and reliably amplify unknown genomic DNA using our patented APA technology: 1. Isolate unknown genomic sequences flanking transgenes (including T-DNAs, gene traps, transposons), sequence-tagged sites (STSs) or expressed sequence tags (ESTs). 2. Isolate localized sequences flanking known sequences from large clones and genomic DNAs. 3. Sequence insert ends of large clone…

ASH is APA-based, full-length-enriched, single-stranded cDNA subtraction hybridization library. - ASH cDNA subtraction is full-length-enriched and independent of PCR suppression. - ASH cloning is directional and does not involve normalization. - ASH method provides non-exponential amplification before subtraction because double-stranded cDNA is not required. - ASH method has a better subtraction effect because 1) a high ratio…

Bio S&T's high-quality RNA can be used directly for NxGen RNA sequencing as well as other downstream applications that require optimal-quality RNA such as quantitative real-time RT-PCR, microRNA cloning and amplification and Northern blotting.

Fosmid clones are similar in size (ca. 40kb) to cosmids, but, like BAC clones, they contain replicons derived from the F factor for DNA replication and segregation. Because of this property, they are present in low copy number and consequently more stable than cosmids. Also, the copy control vector can be used for easy DNA purification from fosmid clones. Fosmid libraries are commonly used for closing gaps in a whole genome se…

Bio S&T is the only commercial provider of highly purified human tRNAs. RNA is most widely used as the primer of retroviral reverse transcriptases. The 3’ end of the tRNA binds to the complementary binding site on the viral RNA therefore initiating reverse transcription. 1. tRNALys3 is the primer of HIV-I, HIV-II, SIV and FIV. 2. tRNALys1,2 are the primers of BLV, HTLV-I and II, SSV, FLV, VV, CAEV, MPMV, SMR and EIAV. 3. tRNAT…

RealTime ready Custom RT-qPCR Assays and Panels Get a head start on your gene expression analysis with function tested assays for all annotated human, mouse, and rat genes Achieve high specificity using intron-spanning assays based on short hydrolysis LNA-substituted Universal ProbeLibrary (UPL) Probes.  Rely on stringently RT-qPCR-tested assays that are compliant with MIQE (Minimum Information for Publication of Quantitati…

Discover More, Sequence Less Built upon the NimbleGen Sequence Capture empirically optimized probe design algorithm with high efficiency uniformity of capture1, and now with expanded coverage of coding exons, SeqCap EZ Exome v3.0 offers increased performance. Capture the most comprehensive picture of the human exome with SeqCap EZ Exome Library v3.0. Based on the latest database builds and offering a 64Mb sequence capture, Seq…

The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…

The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…