Waters Drug discovery > Lead Discovery Products & Reviews

Separating the signal from the noise. PFAS Solution Installation Kits provide everything  you need to get your analytical system PFAS ready.  

Waters and ERA are dedicated to helping you meet regulatory requirements and establish sensitive, robust and reproducible workflows in your lab.  Ensuring quality at every turn in your workflow, Waters ERA deliver reference materials you need to be confident about your data.

Designed to meet the everyday challenges facing pharmaceutical quality control (QC) labs, the Alliance™ iS HPLC System delivers a new era of intuitive simplicity by reducing errors with innovative system intelligence, enhancing productivity with safeguards to ensure system performance, and maximizing system uptime. 

With Waters simple-to-use Automation Portal, you can easily automate your ACQUITY and Arc UPLC, UHPLC, and HPLC Systems and maximize your lab’s efficiency – minimizing tedious manual procedures in your LC workflows, improving lab throughput, reducing analyst errors, and freeing up time to focus on your science.

More than just a column - A solution providing application-focused standards, methods, and exclusive support so you can easily and reliably achieve state-of-the-art separations.

High Resolution 5 µm particle for Anion-exchange SAX) HPLC of nucleic acids

Reversed-Phase nano columns for proteomics

High efficincy low adsorption hardware for aggregate analysis of Adeno Associated virus (AAVs) and small to medium nucleic acids.

High Resolution 2.5 µm particles for Anion-exchange (WAX) HPLC of nucleic acids

IEX, SEC, RP, and HIC columns for Proteins and Peptides 

Size Exclusion Column for mAbs

Cation-Exchange Column for mAbs

High resolution XBridge Oligonucleotide BEH C18 OBD Prep Column, 130Å, 2.5 µm for purfication of oligo nucleotides.

Size-based separations of peptides. proteins, and viral vectors

Size-based separations of peptides, proteins, and viral vectors

Reversed-phase based separations of peptides

The Atlantis® T3 HPLC columns set the standard for retention and separation of polar compounds via reversed-phase HPLC. Atlantis® T3 columns are a universal, silica-based, reversed-phase C18 line of HPLC columns that not only retain and separate small, water-soluble polar organic compounds, but also provide superior performance across a wider pH range. Atlantis® columns are the culmination of over 30 years of bonded phase rese…

The ChromaLynx™ Application Manager automates the processing of LC/MS or GC/MS and LC/MS/MS or GC/MS/MS data. While the high chromatographic separation efficiency and narrow peak widths typical of GC/MS often increase the challenge to identify co-eluting components, ChromaLynx facilitates the rapid detection, identification and semi-quantitative determination of all components. Manually reviewing complex chromatograms to locat…

Market Leading LC-TOF-MS with Unrivalled Sensitivity, Exact Mass and Dynamic Range for Qualitative Applications The Waters LCT Premier™ XE is the market-leading orthogonal acceleration time-of-flight (oa-TOF) benchtop mass spectrometer for LC applications. Based on proven and reliable technology, the LCT Premier XE provides unrivalled all round performance for those challenging LC/MS applications. The LCT Premier XE's high sen…

Achieve faster run times and improved sensitivity with a smaller particle size

SunFire™ columns feature excellent low pH stability and improved column lifetime compared to many silica-based HPLC column brands. SunFire columns are packed with state-of-the-art silica and new proprietary C18 and C8 bonding and endcapping for high efficiency, resulting in greater sensitivity.  SunFire columns are manufactured to achieve the highest level of chromatographic consistency column-to-column and batch-to-batch. MS-…

Excellent low pH stability and high mass loading capability

ACQUITY UPLC® BEH C18 and C8 columns were designed to be the universal columns of choice for most UPLC® separations by providing the widest pH range.They incorporate trifunctional ligand bonding chemistries which produce superior low pH stability and ultra-low column bleed. This low pH stability is combined with the high pH stability of the 1.7 µm BEH particle to deliver the widest usable pH operating range. In addition, these…

ACQUITY UPLC® BEH Shield RP18 columns combine Waters patented Shield Technology* with BEH Technology™ by incorporating an embedded carbamate group into the bonded phase ligand.Waters shield ligands consistently demonstrate increased retention of phenolic compounds versus straight chain alkyl columns. The alternate selectivity and excellent peak shape from the embedded polar group ligand, when combined with the wide pH range an…

ACQUITY UPLC® BEH Phenyl columns utilize a trifunctional C6 alkyl tether between the phenyl ring and the silyl functionality. This ligand, combined with the same proprietary endcapping processes as the ACQUITY UPLC™ BEH C18 and C8 columns, provides ultra-low column bleed, long column lifetimes and excellent peak shape. This unique combination of ligand and endcap on the 1.7 μm BEH particle creates a new dimension in selectivi…