Monolith His-Tag Labeling Kit RED-tris-NTA
NanoTemper TechnologiesHis-Tag specific labeling for MST using RED-tris-NTA
NanoTemper Technologies Products & Reviews
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NanoTemper Technologies – We care about your research We develop highly innovative instrument and software solutions for biomolecular analysis. Our global application centers ensure unparalleled customer care and support. Excellence. Focus. Passion. For your research. For Affinity. Stability. Conformation. At NanoTemper Technologies, we are passionate about achieving excellence in everything we do. This has made us the partner of choice for thousands of researchers worldwide in the pharmaceutical and biotechnology industries as well as in academic settings. Our collaborative approach, science-driven insights, and high-quality, proprietary instruments and analytical technologies focus on helping researchers make the greatest impact – with maximum speed, efficiency and precision. A dedicated team of experts operates globally to offer you and your team individual application support and to ensure maximum instrument capability. Wherever you are, regardless of your focus...we care about your research. NanoTemper Technologies is a market leader in providing high-quality instruments for biomedical research. The company’s products are used by thousands of scientists across four continents. With headquarters in Munich, Germany, and subsidiaries in the UK, Poland, US, Brazil and India, the company is rapidly expanding worldwide. Among others, NanoTemper Technologies has been awarded the German Innovation Award 2012, the Bavarian Export Prize 2013 and the Deutscher Gründerpreis (German Founders Award) 2014. NanoTemper Technologies develops, produces and markets technologies and instruments for biomolecular analytics, from basic to preclinical research. The high-quality instruments are based on proprietary and innovative technologies: Monolith: The Efficient Performer MicroScale Thermophoresis (MST) technology is a unique method to study binding affinities in an easy, fast and precise way. Four Monolith Series instruments were introduced since 2010. Seismos: The In-Depth Explorer The recently acquired Surface Acoustic Wave (SAW) technology measures binding kinetics, and is sensitive to both mass and conformational changes Prometheus: The Stability Expert In 2015, a novel product line represented by the Prometheus NT.48 instrument was launched offering nanoDSF technology. This is the method of choice for measuring ultra-high-resolution protein stability in native conditions using intrinsic tryptophan and tyrosine fluorescence. Visit NanoTemper Technologies to learn more about the MST, SAW and nanoDSF technologies. Schedule an instrument demonstration and explore the benefits of NanoTemper’s devices with your own samples.
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Prometheus Panta for biologics stability profiling with particle sizing and molecular weight determination by NanoTemper Technologies
NanoTemper TechnologiesPrometheus Panta monitors the thermal stability, turbidity, and dispersity of a protein sample, and provides the highest-resolution, highest-quality data for ranking and selecting candidates. Prometheus Panta outputs critical quality parameters about your therapeutic proteins of interest, including: their hydrodynamic radius, molecular weight, self-association propensity, and deltaG of unfolding.
Dianthus for challenging affinity screening
NanoTemper TechnologiesDianthus is a plate-based, microfluidics-free affinity screening platform that measures under controlled equilibrium conditions and in-solution. With two biophysical modalities - Spectral Shift and TRIC - Dianthus excels at challenging interactions that involve molecules like PROTAC ternary complexes, intrinsically disordered proteins, and fragment libraries.
Monolith X for Immobilization-Free Binding Affinity Measurements
NanoTemper TechnologiesMonolith X is a capillary-based system that enables you to measure the strength of molecular interactions in solution, without the need for immobilization. Minimal impact fluorescent labelling empowers you to measure Kds between a wide variety of targets and ligands using low amounts of sample. Enjoy approachable assay development with a fully guided process embedded in the default software.
Prometheus Panta + RA for High Throughput Stability Characterization
NanoTemper TechnologiesPrometheus Panta + RA monitors the thermal stability, turbidity, and dispersity of a protein sample. It also measures the hydrodynamic radius, molecular weight, and self-association propensity of your protein-based therapeutics for developability profiling. The Panta uses dye-free, buffer-independent measurements from nanoDSF (nano Differential Scanning Fluorimetry), DLS (Dynamic Light Scattering), and backreflection technolo…