Merck Drug discovery > Target Discovery Products & Reviews

• Concentrates 500 µL down to 15 µL• Concentration factor 25 x to 30 x• High sample recovery (greater than 90% of dilute starting solution)• Fast processing time - 10 to 30 minutes• Consistent recoveries thanks to the reverse spin capability• Reverse spin capability provides consistent recoveries

Microbiology tested, suitable for plant cell culture, suitable for cell culture, powder.

This In Vitro Vascular Permeability Assay kit employs a 96-well plate, and provides an efficient system for evaluating the effects of chemicals & drug compounds on endothelial cell adsorption, transport & permeability. 96-Well Permeability Insert Assembly, Collagen-coated: One 96-well receiver tray containing 96 connected porous cell culture inserts pre-coated with type I rat-tail collagen. Receiver Tray, 96-Well: Two…

The ChIPAb+ EZH2, clone AC22 antibody/primer set includes the EZH2, clone AC22 antibody, a negative control antibody (purified mouse IgG), and qPCR primers which amplify a 135 bp region within the promoter of the human MYT-1 gene. The EZH2, clone AC22 antibody and negative control antibodies are supplied in a scalable "per ChIP" reaction size and can be used to functionally validate the precipitation of EZH2-associated chromat…

The Cell Proliferation Kit I (MTT) is a colorimetric assay for the non-radioactive quantification of cellular proliferation, viability, and cytotoxicity.

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits: A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD)…

Estapor® Red Intense Microspheres COOH PS 5%

Estapor ® Red Intense Microspheres COOH PS 5%

Europium Fluorescent Functionalized Microspheres

Europium Fluorescent Functionalized Microspheres

Europium Fluorescent Functionalized Microspheres

Sterivex-GP Pressure Sterile Filter Unit.

Steripak-GP filter units are designed for larger scale pressure-driven filtration of tissue culture media with or without serum. They are single use and are not autoclavable. The filter units come in two sizes, with the smaller unit able to filter up to 10 L and the larger up to 20 L. Both sizes utilize the low protein binding, fast flow 0.22 µm EMD Millipore Express membrane.

Steritop bottle top filter units provide a large filter area for rapid sterile filtration of aqueous fluids into narrow-mouth (33 mm) or wide-mouth (45 mm) bottles. A small tab inside the funnel secures an optional prefilter in-place during filtration. For added protection against contamination, the threads for bottle attachment have been slightly recessed in case the funnel accidentally touches a work surface

33 mm diameter sterile syringe filters.

With Millicell inserts, attachment or suspension cells can access media from both their apical and basolateral sides. Cell growth, structure, and function more closely mimic what occurs in vivo. In addition, Millicell inserts make it possible to study both sides of the cell monolayer. Millicell inserts are available for 24-, 12-, or 6-well plates.

Millicell® cell culture insert plates are a patented device designed to support cell growth and differentiation of endothelial and epithelial cell lines, including CaCo-2. The Millicell® device is available with a 0.4 µm PCF and a variety of PET membrane pore sizes. The plate is designed for maximum user convenience and incorporates features such as apical assist for easier pipetting and basolateral access.

Each Millicell® HY (high yield) flask provides a consistent, quality growth environment across all layers, with the same volume of media in each layer. Recovering cells is as easy as growing them. With easy access to pipetting or pouring, Millicell® HY flasks deliver reproducible, high yields of healthy cells. Plus, they’ve been tested for use with stem cells.

Simplify your cell analysis by using the Millicell® EZ SLIDE to culture, fix, stain and view your sample all in one device. There’s no need to remove the media chamber from the slide prior to fixing or staining. Easily remove wells without worrying about breaking slides or harming cells. Acquire data simply and quickly with Millicell® EZ SLIDEs.

MultiScreen® plates with 96- and 384-well capacities, available in a varity of configurations and a diverse set of housing materials, assuring compatibility with varied media formulations and solvents. Solid bottom plates are available for chemiluminescent and fluorescent screening assays, sample preparation and storage, and ELISA including 8-well strip format.

The Stericup® Quick Release 500 ml vacuum filter is a filter bottle system ideally suited for sterile filtration of cell culture media, buffers and reagents, that includes a Steritop® fiter unit with a re-designed Stericup® Quck Release receiver bottle.  It is the next generation of the original Stericup® Sterile Vacuum Filtration System- a staple in labs around the world for decades.

The Stericup ® E and Steritop ® E sterile filtration devices—evolved with an eco-conscience. This progressive rethinking of filter design helps to reduce your lab’s environmental impact.

Top TEER Monitoring.

Predesigned probe assays for gene expression analysis

Broad portfolio of products for knockdown of gene expression