Merck Life Sciences Products & Reviews

Adiponectin is identified as a 30 kDa adipokine that is secreted from the adipose tissue into circulating blood and influences systemic metabolism.

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Serum Amyloid A3 (SAA-3) is an acute phase protein produced in the liver. In response to injury, granulocytes and macrophages secrete cytokines which modulate the production of acute phase proteins. Many of these proteins, such as SAA-3, α1-acid glycoprotein (AGP), lipoclain 24P3, plasminogen activator inhibitor-1 (PAI-1) and PTX3 are secreted from adipocytes and are elevated in various metabolic disease states.

Adiponectin is identified as a 30 kDa adipokine that is secreted from the adipose tissue into circulation blood and influences systemic metabolism.

Rat/Mouse Ghrelin (Active) ELISA kit for the quantification of active ghrelin in rat and mouse serum or plasma samples. Each kit is sufficient to measure 39 unknown samples in duplicate.

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

EMD Millipore is pleased to offer the Rat/Mouse C-Peptide 2 ELISA kit for the quantification of C-peptide 2 in rat and mouse serum and plasma samples. Each kit is sufficient to measure 39 unknown samples in duplicate.

Growth Hormone (GH) is a 23 kDa circulating pituitary hormone, Rat GH shares approximately 97% homology with mouse GH and 65% homology with human GH in its protein sequence.

GIP, also known as gastric inhibitory polypeptide, or glucose-dependent insulinotropic polypeptide, is a 42 amino acid peptide hormone synthesized in and secreted from K cells in the intestinal epithelium.

Insulin, a 5.8 kDa hormone, is secreted by the islet beta cells in the pancreas.

The OxyELISA™ Oxidized Protein Quantitation Kit provides a sensitive methodology for detection and quantitation of proteins modified by oxygen free radicals and other reactive species. Oxygen-derived free radicals have been implicated in numerous physiological functions such as apoptosis, cancer, aging, neurodegenerative diseases, chronic inflammatory diseases, pulmonary diseases, and cardiovascular diseases (for reviews, see…

Antipain is a serine and cysteine reversible protease inhibitor. It inhibits papain and trypsin. Plasmin is inhibited to a small extent as well. More specific than leupeptin for papain and trypsin. Source: Microbial origin. Not synthetically made.

Montage Antibody Purification Kits are designed for fast and easy antibody purification from serum, ascites or cell culture supernatants. The kits include spin columns pre-packed with high capacity PROSEP-A or G media. There are no pumps to setup. No columns to pack. All you need is a centrifuge to purify 10–20 mg in less than 60 minutes.The protocol is easy to follow and, unlike traditional gravity flow methods, the use of ce…

With their vertical membrane design, Amicon Ultra 0.5 mL filters deliver great performance and lower spin timesConcentrates 500 µL down to 15 µLConcentration factor 25 x to 30 xHigh sample recovery (greater than 90% of dilute starting solution)Fast processing time - 10 to 30 minutesConsistent recoveries thanks to the reverse spin capabilityReverse spin capability provides consistent recoveries

Concentrates 2 mL down to 15-70 µL 98% sample recovery Fast processing time - 10 to 30 minute spin times Engineered dead stop Reverse spin capability provides consistent recoveries

Automation compatible filter units from EMD Millipore are specially designed to provide efficient filtration for dissolution and other automated sample preparation applications.Choice of Filter Media: Automation compatible filter units are available in a variety of membrane types and pore sizes, including units with prefilters for particulate-laden samples.Automation Compatible Packaging: The 200 pack comes preassembled in 8 t…

Millex filter units with hydrophobic Fluoropore membrane are ideal for sterilizing gases, venting sterile containers, and sterilizing or clarifying organic solutions. Specialized filter units protect hemodialysis transducers from blood and moisture. 50 mm Millex filter units are also used for vacuum line protection. All units are bi-directional

Sample preparation for ion chromatography

Filter particle-laden or viscous samples

This 13 mm syringe filter with a Hydrophilic Polyethersulfone membrane, for non-sterile filtration, has a 0.45 micron pore size used in preparation of aqueous & mild organic solutions prior to chromatography or other instrument analyses.

4 mm syringe filter with a Hydrophilic PVDF membrane, for non-sterile filtration, has a 0.22 µm pore size used in fine particle removal from aqueous & mild organic solutions.

Millex-GP Filter for Samplicity G2, 0.22 µm, PES 33 mm, non-sterile

Bløk Noise Cancelling Reagents are designed especially for Western blotting applications. This family of protein-free, ready-to-use buffers has been optimized to reduce background levels when using chemiluminescence, fluorescent, or phosphotyrosine detection. Bløk buffers are ideal for use with Immobilon®-P Western blotting membranes and the SNAP i.d.® system, and are also compatible with standard Western blotting techniques.

The Luminata ELISA HRP chemiluminescent substrates provide three major advantages:High sensitivity for detecting as little as 0.1 pg of proteinBroad dynamic detection range (up to 2,500-fold), enabling a wide range of quantitation.Flexibility to adjust ELISA signal strength

The MILLIPLEX®MAP Human Soluble Cytokine Receptor - Premixed 14 Plex is used for the simultaneous quantification of the following Human analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4), sEGFR