Merck Drug discovery > Basic Research Products & Reviews

Proinsulin, the precursor of insulin and C-peptide, is made by the beta cells of the pancreas. This kit measures only the intact form of human proinsulin

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Proinsulin, the precursor of insulin and C-peptide, is made by the beta cells of the pancreas. This kit measures the intact and intermediate metabolic forms of human proinsulin.

This Human Pancreatic Polypeptide (PP) ELISA kit is used for the non-radioactive quantification of Human PP in human serum, plasma, tissue extract and cell culture samples. One kit is sufficient to measure 39 unknown samples in duplicate

Adiponectin is identified as a 30 kDa adipokine that is secreted from the adipose tissue into circulating blood and influences systemic metabolism.

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Serum Amyloid A3 (SAA-3) is an acute phase protein produced in the liver. In response to injury, granulocytes and macrophages secrete cytokines which modulate the production of acute phase proteins. Many of these proteins, such as SAA-3, α1-acid glycoprotein (AGP), lipoclain 24P3, plasminogen activator inhibitor-1 (PAI-1) and PTX3 are secreted from adipocytes and are elevated in various metabolic disease states.

Adiponectin is identified as a 30 kDa adipokine that is secreted from the adipose tissue into circulation blood and influences systemic metabolism.

Rat/Mouse Ghrelin (Active) ELISA kit for the quantification of active ghrelin in rat and mouse serum or plasma samples. Each kit is sufficient to measure 39 unknown samples in duplicate.

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

EMD Millipore is pleased to offer the Rat/Mouse C-Peptide 2 ELISA kit for the quantification of C-peptide 2 in rat and mouse serum and plasma samples. Each kit is sufficient to measure 39 unknown samples in duplicate.

Growth Hormone (GH) is a 23 kDa circulating pituitary hormone, Rat GH shares approximately 97% homology with mouse GH and 65% homology with human GH in its protein sequence.

GIP, also known as gastric inhibitory polypeptide, or glucose-dependent insulinotropic polypeptide, is a 42 amino acid peptide hormone synthesized in and secreted from K cells in the intestinal epithelium.

Insulin, a 5.8 kDa hormone, is secreted by the islet beta cells in the pancreas.

The OxyELISA™ Oxidized Protein Quantitation Kit provides a sensitive methodology for detection and quantitation of proteins modified by oxygen free radicals and other reactive species. Oxygen-derived free radicals have been implicated in numerous physiological functions such as apoptosis, cancer, aging, neurodegenerative diseases, chronic inflammatory diseases, pulmonary diseases, and cardiovascular diseases (for reviews, see…

Antipain is a serine and cysteine reversible protease inhibitor. It inhibits papain and trypsin. Plasmin is inhibited to a small extent as well. More specific than leupeptin for papain and trypsin. Source: Microbial origin. Not synthetically made.

With their vertical membrane design, Amicon Ultra 0.5 mL filters deliver great performance and lower spin timesConcentrates 500 µL down to 15 µLConcentration factor 25 x to 30 xHigh sample recovery (greater than 90% of dilute starting solution)Fast processing time - 10 to 30 minutesConsistent recoveries thanks to the reverse spin capabilityReverse spin capability provides consistent recoveries

Concentrates 2 mL down to 15-70 µL 98% sample recovery Fast processing time - 10 to 30 minute spin times Engineered dead stop Reverse spin capability provides consistent recoveries

Bløk Noise Cancelling Reagents are designed especially for Western blotting applications. This family of protein-free, ready-to-use buffers has been optimized to reduce background levels when using chemiluminescence, fluorescent, or phosphotyrosine detection. Bløk buffers are ideal for use with Immobilon®-P Western blotting membranes and the SNAP i.d.® system, and are also compatible with standard Western blotting techniques.

The Luminata ELISA HRP chemiluminescent substrates provide three major advantages:High sensitivity for detecting as little as 0.1 pg of proteinBroad dynamic detection range (up to 2,500-fold), enabling a wide range of quantitation.Flexibility to adjust ELISA signal strength

The MILLIPLEX®MAP Human Soluble Cytokine Receptor - Premixed 14 Plex is used for the simultaneous quantification of the following Human analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4), sEGFR

The MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel II - Premixed 23 Plex is used for the simultaneous quantification of the following Human analytes: 6Ckine, BCA-1, CTACK, ENA-78, Eotaxin-2, Eotaxin-3, I-309, IL-16, IL-20, IL-21, IL-23, IL-28a, IL-33, LIF, MCP-2, MCP-4, MIP-1d, SCF, SDF-1A+β, TARC, TPO, TRAIL, TSLP

The MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel III - Premixed 11 Plexis used for the simultaneous quantification of the following Human analytes: GCP2, HCC-1, I-TAC, IL-11, IL-29, Lymphotactin, M-CSF, MIG, MIP-3α, MIP-3β, NAP2

The MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel III - Premixed 9 Plex is used for the simultaneous quantification of the following Human analytes: GCP2, I-TAC, IL-11, IL-29, Lymphotactin, M-CSF, MIG, MIP-3α, MIP-3β

The MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel II is used for the simultaneous quantification of the following Human analytes: 6Ckine, BCA-1, CTACK, ENA-78, Eotaxin-2, Eotaxin-3, I-309, IL-16, IL-20, IL-21, IL-23, IL-28a, IL-33, LIF, MCP-2, MCP-4, MIP-1d, SCF, SDF-1A+β, TARC, TPO, TRAIL, TSLP