ESA provides the highest performing specialty detectors for HPLC, UHPLC and EC-MS applications. Introducing the Corona® ultra™ the new charged aerosol detector that is now truly UHPLC compatible and suited for diverse applications from small molecules and carbohydrates to lipids and polymers. The Corona ultra delivers reduced time for method development, increased throughput and approximately 5 times lower solvent consumption. The Corona CAD® continues to be the proven workhorse for Pharma QC. ESA is the leader in Electrochemical Detection for HPLC with the Coulochem® III and CoulArray® detectors which deliver superior bio-analytical detection capabilities. ESA electrochemical technologies have been adapted for use with mass spec as a tool for drug development and metabolism. ESA offers a complete line of HPLC systems, advanced specialty detectors, specialized LC components, innovative software products, reagents, expert technical assistance and analysis services.
CoulArray® - The Only Coulometric Array Detector for HPLC ESA's pioneering electrochemical technology has made possible the multi-sensor detector for HPLC. Measure multiple analytes simultaneously, including those that are chromatographically unresolved. Only ESA's unique coulometric array detection provides: Sensitivity to femtomole levels 3D resolution of co-eluting peaks Qualitative characterization of peaks Simpl…
Coulochem® III Electrochemical Detection Platform Both Coulometric and Amperometric detection Available with DC and/or Pulse/Scan modes (or both) Compatible with all HPLC columns Ideal for methods development or routine applications requiring high-sensitivity detection of a single or small group of analytes Sensitive, flexible and exceptional stabilty
For Identification and Measurement of Physiologically Relevant Small Molecules The ESA Metabolomics® System provides the ability to study a variety of molecules quickly and accurately: • Measure Large Numbers of Molecules • Simultaneously Assess and Measure Xenobiotics and their effects • Compounds, Metabolites and Endogenous Compounds • Compatible with Pattern Recognition Software • Study Patterns of Individual Markers ESA…
Coulometric Electrochemical Cells- The Key to Enhanced Selectivity Coulochem cells are unique in their design, employing the patented ESA flow-through porous graphite electrode. These low-volume analytical cells contain two working electrodes. The high surface area of each electrode results in 100% reaction of the electroactive compound. The first (screening) electrode can be used to eliminate potentially interfering com…
Double-beam, variable wavelength capability Programmable wavelengths: 190 - 900 nm East-to-use Control Pad Available Lamp startup/shutdown Pre-aligned lamps for easy changeover Remote autozero capability Optimized for use with ESA Coulometric electrochemical detection Low noise and low drift for increasing sensitivity and stability in analyses. The Model 526/528 detectors provide extremely low operating noise levels…
A low volume electrochemical cell optimized for the low flow rates of electrospray ionization mass spectrometry (ESI-MS). • Optimized for incorporation into low flow rate LC-MS applications • Provides high efficiency electrochemical conversion with minimal peak dispersion Proven Coulometric DesignThe Model 5030 Cell utilizes the proven porous graphite flow through design pioneered by ESA and is optimized for incorporation…
