AutoMate Scientific Inc. Drug discovery > Basic Research Products & Reviews

Culturing Cylinders are used to barricade cells or suspended specimens in a Delta T® Culture Dish or to restrict and concentrate the growth and location of cells plated on an FCS2® Coverslip. They are 5mm high and available in a variety of inside diameters including 1mm, 2mm, 4mm, 6mm, 8mm, 10mm, and 12mm. The outer diameter is always 2mm greater than the inside diameter due to the 1mm wall thickness. The cylinders are made of…

To eliminate the heat loss from the specimen, Bioptechs developed a patented Objective Heater System®, which includes a heater/sensor and an electronic controller specifically designed for this purpose. The heater/sensor is comprised of an adjustable thin-film heating band which surrounds 3/4 of the diameter of the upper region of the central retracting tube of the objective. A temperature probe positioned in the gap formed be…

A closed system, parallel plate, micro-environmental chamber for upright microscopes. The FCS3 provides the user with all of the functionality of the popular FCS2 but redesigned for upright microscopes. Therefore, you have the following attributes in one easy to load and use chamber:•Suitable for no flow through high rate flow procedures where a rapid exchange of media is required with low cell surface shear•Cell temperature c…

Brief pulses of electricity are used in various biomedical research applications as a stimulus to excite nerve or muscle fibers. Several factors need to be considered when choosing the right stimulator.The DS2A Mk.II provides a precise Constant Voltage stimulus (up to 100V) controllable in Pulse Duration and Amplitude from self-contained batteries, making it ideally suited to electrophysiological recording in small preparation…

Brief pulses of electricity are used in various biomedical research applications as a stimulus to excite nerve or muscle fibers. Several factors need to be considered when choosing the right stimulator.The DS3 provides a precise Constant Current stimulus (up to 32mA) controllable in Pulse Duration and Amplitude and as with the DS2A this output comes from self-contained batteries. The DS3 also features a "clamp" or discharge c…

The DS4 takes an analogue voltage waveform defined within your own data acquisition/ control system and converts it into an isolated constant current stimulus. The DS4 will accept several input voltage ranges and produces four output ranges (±10µA, ±100µA, ±1mA and ±10mA). It also features a GATE input, so that several DS4 units can be controlled by a single analog waveform, but enabled individually via this GATE input. A t…

Combination of a cell culture dish and a cover slip for imaging inside a channel• 100µl channel – small volume• suited for immunofluorescence • real time imaging during staining process• available with elastic surface• large observation area for microscopy• high resolution microscopy of living and fixed cells• lids for long term cultivationrecommended volume per reservoir600 µlnumber of channels1volume of the channel100 µlheig…

35mm Petri dish with a thin bottom for high end microscopy – with low walls• ideal cell growth with ibiTreat surface• low walls > cell manipulation combined with high resolution microscopy• lid with lock position for minimized evaporation• perfect cell imaging with fluorescence microscopy and phase contrast• no glue > no cell harm• 3 lid positions adjustable• suitable for DIC (without lid)Ø µ-Dish 35mm, low35 mmrecommended vol…

µ-Slide for stable gradients, 3 chambers on one slide for chemotaxis and migration assays• long term chemotaxis experiments with adherent cells• ready to use system, no assembling• linear gradients, stable for over 48 hours• 3 chambers on one slide for parallel working• adapters for different pipettes• made for high-end video microscopybasic principle: two large reservoirs of 40µl are connected by a narrow observation areathe…

µ-Slide for cell microscopy on or in 3D-gel matrices, providing flat gel surfaces with a minimum of gel used• flat gel surface > all cells in focus• homogeneous 0.8mm thick gel layer• 4 mm well in 5 mm well• use only 10 µl of gel per well+• low evaporation• compatible with multi channel pipettesnumber of wells15volume inner well10 µlØ inner well4 mmvolume upper well50 µlØ upper well5 mmgrowth area per inner well0.125 cm2bottom…

The ITC-18 is the second-generation low-noise 16-bit computer interface from Instrutech Corporation. The ITC-18 offers unsurpassed capability while retaining all of the exceptional features of its predecessor, the ITC-16. The ITC-18 provides a major improvement in the quality of acquired data, making measurements that would otherwise not be possible.* All synchronous analog and digital channels are optically isolated* Eight si…

Computer-controlled microelectrode amplifier with a high-speed current clamp capable of sharp-electrode, field potential or ion-selective measurements, and a patch clamp for whole-cell, excised or cell-attached patches, bilayers, and electrochemistry with voltammetry or amperometry. MultiClamp 700B is shipped with the following,MultiClamp 700B Amplifiero Two 1-CV-7B headstageso US power cord (Part Number 1-3010-0011)o Europea…

The world's smallest patch clamp rig. Providing biggest results. The Port-a-Patch is a one-cell-at-a-time system, which is surprisingly small for a complete patch clamp rig. Patch clamp recordings in the whole cell configuration, and single channel recordings in the cell attached configuration, can be performed with planar patch clamp chips. The Port-a-Patch is routinely provided with an Axon/MDC MultiClamp amplifier or an EPC…

Run dual two-electrode voltage clamp experiments simultaneously:With two additional micromanipulators, the system can perform dual two-electrode voltage clamp (TEVC) experiments simultaneously. Designed to be affordable to the scientific community, this system increases productivity significantly. Additional units can be run in parallel to further increase TEVC throughput.Run up to four patch clamp simultaneously:As each man…

The ez-gSEAL 100A pressure controller is designed mainly for automated patch clamping, but it can also be used for many other applications. With the ez-gSEAL pressure controller, patch clamping becomes as easy as a click of a button. You may use it with our ezPATCH 100A smart manipulator, PatchMAX 100A automated patch clamp system, ChannelMAX 100A Mini automated dual clamp system or ChannelMAX 100A Twin automated quad clamp sy…

Incredibly small footprint:This patent-pending design has an 8" x 8" footprint; it is the smallest multifunction patch clamp system available.  The automated patch clamping system replaces the microscope and the manipulator in the traditional rig. Complete with one automated manipulator, a manual XY stage, a data acquisition board & control system, and a perfusion chamber with the platform, this system can automatically guide…

The NL900D Case & Power Supply unit forms the heart of every NeuroLog System. Modules are not only powered by this unit, but wiring within the case allows signals to be passed between modules without the need for a mass of cable connections through the front panel sockets. The NL900D measures 133mm (high), 483mm (wide) and 317mm (deep).

* Small working volume (* Fast solution exchangeExpression of recombinant receptors in oocytes has been a favorite choice for researchers to assess the pharmacology of recombinant receptors. Since the oocytes are 1-1.5 mm in diameter, however, fast solution exchange around the oocyte was difficult. After several years of electrophysiological research, we have designed a Xenopus oocyte perfusion chamber for use in automated and…

Perfusion chamber, holds 35mm & 50mm Petri dishes (Corning Brand ONLY), or 25mm x 75mm glass slides

Comprehensive electrophysiology data acquisition and analysis software. Provides both sweep-oriented stimulation and continuous data acquisition along with online analysis. Analyses all types of data: patch-clamp I-V, action potentials, minis and single-channel. Includes graphing and layout capability. pCLAMP 10 is shipped with the following:o pCLAMP 10 CD (Part number 1-2700-0167)o pCLAMP 10 USB security key (Part number 1…

* Perfuse cells right in your 35mm Nunc Petri Dish (our default size)Cells cultured in Petri dishes are a popular research tool used in numerous applications, including patch clamping and intracellular ion probe imaging. True perfusion (continuous inflow and outflow) of solutions can be difficult to configure. This forces scientists to plate cells on cover slips for placement into specially designed perfusion chambers. However…

The BSC1 chamber design is similar to the original "Oslo chamber" (Langmoen & Andersen 1981) with later modifications (Dhanjal & Sears 1980, Alger et al, 1984) to allow both interface and submerged methods of slice maintenance.* "Submerged" and "Interface" methods of slice maintenance with same chamber This chamber allows adaptation to either method of slice maintenance simply by altering the fluid level by means of a screw ad…

* "Interface" method of slice maintenance* Dual feed channels for perfusion solution* Use entire surface for multiple slices or templates* Single and dual well templates, other designs available upon request* Single well template has provision for temperature probe and ground wire* Proportional temperature controller (PTC03) with low noise performance used for heating - available separatelyThis slice recording chamber is desig…

This item is the HOLDER (BSKH) and Brain Slice Keeper (S-BSK). * Slices maintained for many hours prior to transfer to recording chamber* Simple to set up and maintain * Slices supported on a quick-change nylon net The Brain Slice Keeper has been designed to pre-incubate brain slices prior to transfer into recording chambers. It consists of a pair of closely fitting acrylic rings, upper and lower, between which is wedged a she…

* Slices maintained for many hours prior to transfer to recording chamber* Simple to set up and maintain * Many slices supported on FOUR quick-change nylon netsThe Brain Slice Keeper 4 has been designed to pre-incubate brain slices prior to transfer into recording chambers. It consists of FOUR pairs of closely fitting acrylic rings, upper and lower, between which is wedged a sheet of nylon netting. In operation, it is totally…