AutoMate Scientific Inc. Drug discovery > Basic Research Products & Reviews

Magnetic base, arms, manifold and tube holders mount everything securely on your microscope stage for electrophysiology and perfusion. The magnetic base of these different StageHands are designed to stick tightly to a steel ring around your perfusion chamber like our QuickStageTM, or any steel surface nearby. They include a 1⁄4-20 screw to insert into a non-magnetic platform or air table. Footprint: 0.75"" (19 mm), adjustable…

For programmable dispensing, microinjection, perfusion or spritzing of reproducible microliter volumes. Pulse a valve quickly for microliter delivery, or leave it on for constant perfusion. The short delivery path saves expensive reagents.• Deliver microliter volumes starting with as little as 100 microliters of precious drugsSwitch between eight solutions in milliseconds from a single tip• Minimize cross-contamination with Ba…

Eliminate electrical interference from any analog signal, without filtering. Ideal for electrophysiology applications like EKG, EMG, and EEGs. Removes 50/60hz noise and harmonics caused by grounding problems, high gain amps, audio equipment, etc.

Bubbles in perfusion systems are caused by solution temperature changes. As solutions warm, they cannot hold as much gas, so they off-gas. This forms bubbles in perfusion tubing. It is especially true in inline heaters where the temperature rises dramatically. The best cure for bubbles is to pre-warm your solutions. AutoMate Scientific introduces the BubbleStop™ Syringe Heater with integrated temperature sensor and feedback. S…

Program your AutoMate Scientific ValveBank® valve and TTL on-off sequences with a Windows 98, 2000, or XP computer using 'click-and-drag' timebars. Save and load unlimited programs to disk, print-out program listings, then download your programs into the ValveBank's memory in one simple step.Features: *Supports up to 16 channels *Open multiple experiment windows *List programs to screen or printer *Supports all ValveBank…

0-10 psi precision pressure regulator, gauge and bubblers for oxygenation or gas saturation of perfusion reservoirs or syringes.Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to a tank/bottle of gas (30 to 100 psi).Elegant design allows individual control of each gas line.

An 8-into-1 multi-barrel manifold with male luer-lock fitting + removable tip available in 100, 250, or 360 micron internal diameter.Applications: *Single-cell and patch superfusion spritzing *Rapid (several millisecond) solution switching *Micro-liter dead volume8 micro-bore internal tubes come ready to connect to 1/16" i.d. tubing.Device is designed to mount in a micromanipulator.Materials: *Polypropylene, polyimide (ny…

Brownlee's rugged yet easy-to-use amplifiers have four channels of a high gain/low noise amplification, lowpass filter and output offset control. A control knob adjusts amplifier parameters, and an alphanumeric LED readout displays values. There is a memory function for each channel. Input voltage noise is only 1.5µV rms.The Brownlee Precision Model 410 is a four-channel general purpose laboratory amplifier (one channel shown)…

In addition to the Model 410 amplifier's features, the Model 440 offers an 8-pole Bessel lowpass filter, auto-zeroing, a line notch filter, highpass filter, multiple memories per channel, and a digital voltmeter on 2 channels. A wide bandwidth of over 500 kHz at all gains insures smooth recordings.The Brownlee Precision Model 440 incorporates four channels of sophisticated amplifier and filter circuitry in a friendly easy-to-u…

Small (approx. 6 x 20 mm) Teflon™ part for combining eight pieces of 1/16" o.d. hard tubing (PE-160 or Teflon) into one outflow. For bath and Oocyte perfusion. Includes built-in flow rate adjustment screw.

Ringstand-mounted HDPE round reservoir. Includes short thumbscrew. Requires AutoMate Scientific Pressurized Perfusion System or pressure source.

Disposable hospital IV flow controller with 1/8" i.d. tubing. Useful for matching perfusion inflow rate to outflow rate.

0-10 psi precision pressure regulator and pressurized syringe holder.For anyone who needs: * Faster liquid-switching * Steady flow rate * Microinjecting * Fine microliter delivery * Small pipette delivery Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to house air or a compressor (30 to 100 psi).Stainless steel construction includ…

Bubbles in perfusion systems are caused by solution temperature changes. As solutions warm, they cannot hold as much gas, so they off-gas. This forms bubbles in perfusion tubing. It is especially true in inline heaters where the temperature rises dramatically. The best cure for bubbles is to pre-warm your solutions. AutoMate Scientific introduces the BubbleStop™ Syringe Heater with integrated temperature sensor and feedback. S…

* Consistent resultsSteady gravity-fed delivery of buffer and fixative results in complete perfusion. * Easy to set up, use and cleanComplete system with everything down to the needles. Fits in standard hoods. * Fraction of the cost of a peristaltic pump and more reliable AutoMate Scientific is providing an option for the scientist who would rather do science than design a system, source parts, phone, buy, etc. Let us take the…

* Consistent resultsSteady gravity-fed delivery of buffer and fixative results in complete perfusion. * Easy to set up, use and cleanComplete system with everything down to the needles. Fits in standard hoods. * Fraction of the cost of a peristaltic pump and more reliable AutoMate Scientific is providing an option for the scientist who would rather do science than design a system, source parts, phone, buy, etc. Let us take the…

* Consistent resultsSteady gravity-fed delivery of buffer and fixative results in complete perfusion. * Easy to set up, use and cleanComplete system with everything down to the needles. Fits in standard hoods. * Fraction of the cost of a peristaltic pump and more reliable AutoMate Scientific is providing an option for the scientist who would rather do science than design a system, source parts, phone, buy, etc. Let us take the…

Perfusion System for real-time or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applicationsIncrease reproducibility with 1 millisecond accuracyValveGuard™ technology detects bad valvesPrevent damage to your ValveLink and easily observe problem valves.Run experiments automatically - even unattendedMicroprocessor-based for accuracy and flexibilityBeca…

MED64 Mobius software is a data acquisition and analysis package for the MED64 multi-electrode array system with an abundant set of analysis functions available both online and offline. It is designed to be easy for beginners and powerful for advanced users. Mobius comes in various packages including “Evoked Potential Measurements” and “Spike Sorter” as well as a combined package.Mobius is flexible software consisting of vario…

• Biological acute or culture preparations are placed directly into the MED64 multi-electrode array probe.• The MED64 probe allows users to stimulate and record samples using 64 planar microelectrodes in an 8 x 8 array embedded in the center of a transparent glass plate.• Arrays are available in four different inter-electrode spacings; 100, 150, 300 and 450 µm enabling measurements of fine detail from small regions to larger s…

Bandwidth of 0.1Hz -10 kHz allows users to record several types of extracellular potentials. • Low-cut filter (High pass filter) with 0.1, 1, 10, and 100Hz cutoff. • High cut filter (Low pass filter) with 1, 2.5, 5, 7.5, and 10kHz cutoff. • Built-in 2-channel stimulator allows users to program and deliver complex stimulation sequences independently through any 2 electrodes. • USB connection to computer.SpecificationsHead Ampl…

Computer-controlled microelectrode current-clamp and voltage-clamp amplifier, useful for a wide range of intracellular microelectrode recording techniques with several modes of operation: two independent current clamp amplifiers with bridge balance, two-electrode voltage clamp, discontinuous current clamp, discontinuous single-electrode voltage clamp, and high-voltage current clamp. Axoclamp 900A is shipped with the following…

Premier patch-clamp amplifier for all patch-clamp configurations, with capacitive-feedback and cooling in the headstage for ultra-low noise single-channel recordings. Axopatch 200B is shipped with the following,o Axopatch 200B amplifiero CV-203BU headstage (Part number 1-CV 203BU)o US Power cord (Part number 1-3010-0011)o European power cord, CEE7/7 (Part number 1-3010-0013)o Accessory kit (Part number1-2050-0301) containing:…

Finally, a culture dish system specifically designed for live-cell microscopy! Now you can have accurate temperature control and high numeric aperture compatibility in a convenient disposable culture dish system compatible with all modes of microscopy. Never before has there been so many capabilities integrated into a specimen control system. • Easily adapted to a variety of specimen types from monolayered adherent cells to t…

Chamber, Controller, 5 Microaqueduct slides, 30 piece gasket set, 50 - #1.5 coverslips. The Objective Heater and Objective Heater Controller is optional (needed for use of high numeric aperture objectives). The objective heater is mounted to the upper end of the central retracting tube of the objective. The standard size fits diameters between 17 and 28mm. The medium size fits diameters between 23 and 29mm. There is also a la…