Agilent Technologies Drug discovery > Target Discovery Products & Reviews

The Agilent SureScan Dx Microarray Scanner is CE-marked for in vitro diagnostic (IVD) use in many countries outside the US. The SureScan Dx Microarray Scanner is Class II, 510(k) exempt in the US. The highly sensitive system has a small physical footprint enabling lab space to be optimized while improving sensitivity and maintaining the broadest dynamic range (XDR).

The Agilent Ozone Barrier Slide Cover provides protection from ozone-induced dye degradation for microarrays. Ozone-induced dye degradation is known to impact cyanine-5, cyanine-3 and dyes of matching wavelengths, affecting the accuracy and stability of analysis.

Our single-stranded DNA binding standard is a helix-destabilizing E. coli protein. The 75.6-kD protein is essential for replication, recombination, and repair processes.

The HybriZAP-2.1 two-hybrid vector system, a eukaryotic system to detect proteinprotein interactions in vivo, provides a method for the rapid identification of genes encoding proteins that interact with a bait protein. The system is based on the ability to separate eukaryotic transcriptional activators into two separate domains, the DNA binding domain (BD) and the transcriptional activation domain (AD).  Detects protein-prote…

The High-Sensitivity beta-Galactosidase Assay Kit provides an easy, rapid, and sensitive method for determining the beta-galactosidase activity in the lysates of cells transfected with a beta-galactosidase expression construct.  Rapid, simple and sensitive  >= 10-fold increase in sensitivity over ONPG-based kits  Reduces amount of cell extract needed for assay  Useful for cells that are difficult to transfect and have l…

The pET E.coli expression system is a widely used in vivo bacterial expression system due to the strong selectivity of the bacteriophage T7 RNA polymerase for its cognate promoter sequences, the high level of activity of the polymerase, and the high efficiency of translation mediated by the T7 gene.  Tightly controlled T7 RNA polymerase-based gene expression in     E.coli    High-level expression upon induction  Convenien…

The pET E.coli expression system is a widely used in vivo bacterial expression system due to the strong selectivity of the bacteriophage T7 RNA polymerase for its cognate promoter sequences, the high level of activity of the polymerase, and the high efficiency of translation mediated by the T7 gene.  Tightly controlled T7 RNA polymerase-based gene expression in     E.coli    High-level expression upon induction  Convenien…

The InterPlay adenoviral TAP System combines our unique tandem affinity purification (TAP) system with our exclusive adenoviral gene delivery system, the AdEasy Adenoviral Vector System for enhanced gene delivery to a broader range of mammalian cells, higher protein yields, and improved purification and analysis of endogenous interacting protein partners.

The InterPlay adenoviral TAP System combines our unique tandem affinity purification (TAP) system with our exclusive adenoviral gene delivery system, the AdEasy Adenoviral Vector System for enhanced gene delivery to a broader range of mammalian cells, higher protein yields, and improved purification and analysis of endogenous interacting protein partners.

Agilent’s proprietary Stabilization and Drying Solution is optimized to reduce degradation of cyanine 3 and 5 by ozone during microarray processing in preparation for scanning. 

The LacSwitch II inducible mammalian expression system utilizes an improved vector system in which several elements of the lac operon have been modified for use in eukaryotic cells for the control of gene expression. The establishment of a highly regulated expression system in eukaryotic cells is an invaluable tool for the study of cell cycle, oncogenicity, cytogenicity, and the mechanisms of gene regulation.

G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. G418 Sulfate is available as a crystalline solid or in aqueous sterile solution.

RNase Block Ribonuclease Inhibitor is a 50-kDa protein that specifically inhibits common eukaryotic RNases including RNase A, RNase B, and RNase C. 

RNace-it ribonuclease cocktail is a mixture of two RNases: RNase A and a nonspecific RNase from Aspergillus oryzae. The combined action of these ribonucleases results in the degradation of RNA into small oligoribonucleotides.  Mixture of RNase A and RNase T1  Combined action of these RNases degrades RNA into small oligoribonucleotides  Tested to be free of contaminating DNase activity

The Affinity protein expression and purification system provides a simple, gentle, and effective method for high-level protein expression and purification. A complete Affinity protein expression and purification system includes calmodulin (calcium-modulated protein or CaM) affinity resin and pCAL expression vectors, containing a calmodulin-binding peptide (CBP) tag.

Agilent’s mouse CpG microarrays enable a comprehensive insight into the DNA methylation changes that may be correlated to key biological processes. Such processes include cancer, development, genomic imprinting, gene silencing, and chromatin stability.

Choose the Klenow Fill-In Kit to perform both partial fill-in reactions to prepare genomic DNA for insertion into the Lambda FIX II vector, and complete fill-in of a 5 overhang to generate blunt ends, to allow direct ligation. Or, use the kit to radioactively end label a 5 overhang with [alpha- 32 P]dNTP.

The Luciferase Assay Kit provides rapid, sensitive, and quantitative measurement of American firefly (Photinus pyralis) luciferase activity in cultured mammalian cells.  Sensitive, widely used reporter assay  Rapid, quantitative results  Reporter activity immediately available upon translation  Useful in conjunction with PathDetect systems

The Mammalian Two-Hybrid Assay Kit is a powerful method for detecting protein-protein interactions in vivo in mammalian cells. The two-hybrid assay kit utilizes hybrid genes to detect protein-protein interactions via the activation of reporter-gene expression.  Detects protein-protein interactions in mammalian cells  Works well in a variety of mammalian cell lines  Confirms suspected interactions between two proteins or i…

The PCR grade deoxynucleotide mix includes 25 mM of each standard dNTP (GATC) for use with any PCR application, including real-time quantitative PCR. These reactions buffers contain the optimal magnesium concentration for efficient PCR.

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…