Active Motif Drug discovery > Target Discovery Products & Reviews

Designed to allow high quality DNA enrichment from as little as 1000 cells per ChIP reaction for abundant targets

Active Motif offers FactorPath™ ChIP-Seq Services to map protein-DNA interactions & histone modifications

Enabling generation of genome-wide binding profiles from as few as 10,000 cells

For use with The LightSwitch™ Luciferase Assay System for analysis of promoter regulation

For use with The LightSwitch™ Luciferase Assay System to measure the impact of a 3´UTR on post-transcriptional regulation

Designed to identify the physical interactions of a miRNA with endogenous mRNA transcripts

Isolating high-quality nuclear, cytoplasmic or whole-cell extract from mammalian cell or tissue samples

Making it possible to perform ChIP in just 1 day

Complete solution for convenient, accurate monitoring of protein/DNA interactions

An optimized and streamlined protocol for high-resolution genome-wide mapping of transcription factor binding sites in the human and mouse genomes

Providing the highest quality ChIP-enriched DNA for analysis by qPCR or Next Generation sequencing

Specially formulated to perform ChIP from PBMCs, including lymphocytes (T cells, B cells and NK cells), monocytes and dendritic cells

Modified ChIP assay that utilizes the CRISPR/Cas9 system to target a specific DNA locus for immunoprecipitation

Highly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity

ELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types

Multiplex epigenetic assay for high throughput profiling of histone post-translational modifications

Asensitive, high-throughput method for quantifying global changes in the level of specific histone modifications

Asensitive, high-throughput method for quantifying global changes in the level of specific histone modifications

Purification of core histones (H2A, H2B, H3 and H4) using very small amounts (as little as 0.9 x 105 cells) of starting material

Screen antibodies, enzymes and proteins for interations with histones and their post-translational modifications

Detect and capture DNA fragments containing 5-hydroxymethylcytosine (5-hmC) DNA methylation for analysis

Immunoprecipitate and enrich for DNA fragments containing 5-hydroxymethylcytosine (5-hmC)

Immunoprecipitate and enrich for single-stranded DNA fragments containing 5-methylcytosine (5-mC)

Fast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA

Novel technology that allows for positive identification of unmethylated DNA fragments