Products & ReviewDrug Discovery & Development
The Kinase Chemogenomic Set (KCGS)
Cancer Tools157681
KCGS is a comprehensive collection of 295 highly selective kinase inhibitors targeting 262 human kinases
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Description
The Kinase Chemogenomic Set (KCGS) is the most diverse and highly-annotated publicly-available collection of kinase inhibitors. This collection was curated to study the ""dark kinases"", which are poorly understood despite their therapeutic potential. The collection includes 295 narrow-spectrum kinase inhibitors that target 262 human kinases. This collection allows for the systematic exploration of kinase signalling networks and identification of novel therapeutic targets.
Key features
- Comprehensive coverage
- Ready-to-use format, supplied in 384-well plate
- Well cited
Applications
- Drug discovery and target validation
- Kinase signalling pathway analysis
- Phenotypic screening
