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SYNTAX System

DNA ScriptAvailable: Worldwide

DNA-on Demand with benchtop convenience and same-day results.

DNA Script

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Description

Introducing the SYNTAX System, the first DNA printer powered by enzymatic synthesis. Designed for ease-of-use, productivity, convenience, and control, the SYNTAX System enables automated nucleic acid synthesis within a benchtop solution. Researchers can now have same-day synthesis of custom oligos at the lab bench, without the need for specialized infrastructure or technical skills, and increased control over their workflows.

System Capabilities

  • Fully automated, walk-away synthesis
  • Plug-and-play integration
  • Parallel synthesis in 96-well plates
  • 15-minute setup time per run
  • Same-day synthesis of up to 30 nt oligos enables two runs in 24 hours
  • Synthesize oligos overnight for next-day use

Oligo Specifications

  • 15 - 60 nt de novo oligo synthesis (A, C, G and T)
  • Custom iDNA length 15 - 40 nt
  • Default 5’-phosphate
  • 200 - 300 pmol per well
  • Normalized to 1 - 5 µM

Applications

Ready-to-use oligos for molecular biology and genomics applications, including

  • endpoint PCR
  • qPCR
  • amplicon sequencing
  • Sanger sequencing
  • site-directed mutagenesis
Webinar

Optimization of a single molecule fluorescence in <i>situ</i> hybridization assay (smFISH) for Drosophila A virus detection

The use of same-day enzymatic synthesis to quickly iterate through probe design to fine-tune sensitivity and specificity has been found to accelerate the optimization of smFISH assays and thus acts as a rapid and simple alternative to immunofluorescence. In this webinar, Dr. Steven Quistad, DNA Script, and Bailey Schmidt, DNA Script, will discuss a recent study carried out in collaboration with the Institut Pasteur using on-demand enzymatic DNA synthesis (EDS) to accelerate the design-print-test-learn cycle required to optimize smFISH assays for the detection of viral RNA in the gut of Drosophila melanogaster.

Key learning objectives

  • Understand the basics of DNA synthesis (EDS) and the SYNTAX System
  • Understand how on-demand EDS probes printed on the SYNTAX System accelerates smFISH assay optimization
  • Understand how generating labeled probes with the SYNTAX System accelerates iteration
  • Discover the advantages of making on-demand DNA with enzymes

Who should attend?

  • Gene expression researchers
  • Genomics researchers
  • Anyone who performs FISH or smFISH assays
  • Anybody who has ever waited on DNA to arrive to start an experiment

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

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