SYNTAX System
DNA-on Demand with benchtop convenience and same-day results.

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Introducing the SYNTAX System, the first DNA printer powered by enzymatic synthesis. Designed for ease-of-use, productivity, convenience, and control, the SYNTAX System enables automated nucleic acid synthesis within a benchtop solution. Researchers can now have same-day synthesis of custom oligos at the lab bench, without the need for specialized infrastructure or technical skills, and increased control over their workflows.
System Capabilities
- Fully automated, walk-away synthesis
- Plug-and-play integration
- Parallel synthesis in 96-well plates
- 15-minute setup time per run
- Same-day synthesis of up to 30 nt oligos enables two runs in 24 hours
- Synthesize oligos overnight for next-day use
Oligo Specifications
- 15 - 60 nt de novo oligo synthesis (A, C, G and T)
- Custom iDNA length 15 - 40 nt
- Default 5’-phosphate
- 200 - 300 pmol per well
- Normalized to 1 - 5 µM
Applications
Ready-to-use oligos for molecular biology and genomics applications, including
- endpoint PCR
- qPCR
- amplicon sequencing
- Sanger sequencing
- site-directed mutagenesis
Optimization of a single molecule fluorescence in <i>situ</i> hybridization assay (smFISH) for Drosophila A virus detection
The use of same-day enzymatic synthesis to quickly iterate through probe design to fine-tune sensitivity and specificity has been found to accelerate the optimization of smFISH assays and thus acts as a rapid and simple alternative to immunofluorescence. In this webinar, Dr. Steven Quistad, DNA Script, and Bailey Schmidt, DNA Script, will discuss a recent study carried out in collaboration with the Institut Pasteur using on-demand enzymatic DNA synthesis (EDS) to accelerate the design-print-test-learn cycle required to optimize smFISH assays for the detection of viral RNA in the gut of Drosophila melanogaster.
Key learning objectives
- Understand the basics of DNA synthesis (EDS) and the SYNTAX System
- Understand how on-demand EDS probes printed on the SYNTAX System accelerates smFISH assay optimization
- Understand how generating labeled probes with the SYNTAX System accelerates iteration
- Discover the advantages of making on-demand DNA with enzymes
Who should attend?
- Gene expression researchers
- Genomics researchers
- Anyone who performs FISH or smFISH assays
- Anybody who has ever waited on DNA to arrive to start an experiment
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.














