Scherzo SM-C18 Column
An ODS column with Anion and Cation Exchange. Weak ionic ligands adequately bonded to this material optimized for the separation of basic/acidic compounds at neutral pH.
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The Scherzo family columns can operate without adding an ion-pairing reagent which is required for conventional ODS columns. In addition, both anionic and cationic compounds are retained on this column. The hydrophobicity of the Scherzo family is similar to that of a conventional ODS colum, so analysis of a compound in combination with a Unison UK-C18 column (conventional ODS phase) will be very effective for method development.
The SM-C18 consists of not only ODS ligands, but also both weak anion ligands and cation ligands which is useful for a wide range of ionic compounds such as salts, vitamins, acidic/ basic compounds, alkaloids etc. It also provides reversed-phase mode, both ion exchange modes, and normal phase mode. Scherzo C18 columns are designed by using the same silica and ODS ligand density as a Unison UK-C18 column. SM-C18 may be effective in changing selectivity when it is difficult to separate impurities on an ODS column.
- Polar and non-polar retention in Reversed Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Unique selectivity of HPLC column
- Wide range of method development possibilities
- Can simultaneous optimize organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reversed Phase + Normal Phase
- Weak ionic ligands adequately bonded to this material optimized for the separation of basic/acidic compounds at neutral pH.
